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Issue 32, 2015
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Microorganism-based monodisperse microcapsules: encapsulation of the fungicide tebuconazole and its controlled release properties

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Abstract

The design of an ideal monodisperse microcapsulation system, which could meet the need for prolonged and better control of drug administration, is a great challenge. Herein cyanobacteria cells served as a natural environmentally-friendly wall material to encapsulate the fungicide tebuconazole (TEB), and then urea–formaldehyde (UF) resins were automatically coated on it via electrostatic interactions. By this means, monodisperse TEB–PCC@UF microcapsules were achieved, which not only can effectively control the drug release rate but also depress the initial “burst effect” to some degree. A bioactivity experiment showed that TEB–PCC@UF microcapsules authentically prolonged the antifungal effects, and were very efficacious in controlling wheat powdery mildew compared with the commercial formulation.

Graphical abstract: Microorganism-based monodisperse microcapsules: encapsulation of the fungicide tebuconazole and its controlled release properties

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Publication details

The article was received on 27 Jan 2015, accepted on 03 Mar 2015 and first published on 04 Mar 2015


Article type: Paper
DOI: 10.1039/C5RA01629K
Author version available: Download Author version (PDF)
Citation: RSC Adv., 2015,5, 25164-25170
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    Microorganism-based monodisperse microcapsules: encapsulation of the fungicide tebuconazole and its controlled release properties

    B. Zhang, T. Zhang, Q. Wang and T. Ren, RSC Adv., 2015, 5, 25164
    DOI: 10.1039/C5RA01629K

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