Issue 3, 2015

Synthesis of (phosphonomethyl)phosphinate pyrophosphate analogues via the phospha-Claisen condensation

Abstract

Pyrophosphate analogues are of great importance especially for the design of biologically active molecules. The phospha-Claisen condensation allows for the rapid synthesis of (phosphonomethyl)phosphinate pyrophosphate analogues and building blocks that can be employed in numerous applications.

Graphical abstract: Synthesis of (phosphonomethyl)phosphinate pyrophosphate analogues via the phospha-Claisen condensation

Supplementary files

Article information

Article type
Paper
Submitted
19 Sep 2014
Accepted
06 Nov 2014
First published
06 Nov 2014

Org. Biomol. Chem., 2015,13, 825-833

Synthesis of (phosphonomethyl)phosphinate pyrophosphate analogues via the phospha-Claisen condensation

F. Gelat, C. Lacomme, O. Berger, L. Gavara and J.-L. Montchamp, Org. Biomol. Chem., 2015, 13, 825 DOI: 10.1039/C4OB02007C

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