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Issue 95, 2015
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Light-triggered chemical amplification to accelerate degradation and release from polymeric particles

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Abstract

We describe a means of chemical amplification to accelerate triggered degradation of a polymer and particles composed thereof. We designed a light-degradable copolymer containing carboxylic acids masked by photolabile groups and ketals. Photolysis allows the unmasked acidic groups in the polymer backbone to accelerate ketal hydrolysis even at neutral pH.

Graphical abstract: Light-triggered chemical amplification to accelerate degradation and release from polymeric particles

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Publication details

The article was received on 27 Jul 2015, accepted on 25 Sep 2015 and first published on 28 Sep 2015


Article type: Communication
DOI: 10.1039/C5CC06143A
Citation: Chem. Commun., 2015,51, 16980-16983
  • Open access: Creative Commons BY license
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    Light-triggered chemical amplification to accelerate degradation and release from polymeric particles

    J. Olejniczak, V. A. Nguyen Huu, J. Lux, M. Grossman, S. He and A. Almutairi, Chem. Commun., 2015, 51, 16980
    DOI: 10.1039/C5CC06143A

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