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Issue 77, 2015
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Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing

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Abstract

Glycopolymer hydrogels capable of mimicking mucosal tissue in mucoadhesion testing have been designed. Liquid formulations containing mucoadhesive polymers were found to be retained on these tissues to the same extent as ex vivo gastric mucosa, when using a dynamic method of assessing mucoadhesion.

Graphical abstract: Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing

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Publication details

The article was received on 25 Mar 2015, accepted on 21 Jul 2015 and first published on 21 Jul 2015


Article type: Communication
DOI: 10.1039/C5CC02428E
Citation: Chem. Commun., 2015,51, 14447-14450
  • Open access: Creative Commons BY license
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    Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing

    M. T. Cook, S. L. Smith and V. V. Khutoryanskiy, Chem. Commun., 2015, 51, 14447
    DOI: 10.1039/C5CC02428E

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