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Issue 6, 2015
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Fluorescence chemosensors for hydrogen sulfide detection in biological systems

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Abstract

A comprehensive review of the development of H2S fluorescence-sensing strategies, including sensors based on chemical reactions and fluorescence resonance energy transfer (FRET), is presented. The advantages and disadvantages of fluorescence-sensing strategies are compared with those of traditional methods. Fluorescence chemosensors, especially those used in FRET sensing, are highly promising because of their low cost, technical simplicity, and their use in real-time sulfide imaging in living cells. Potential applications based on sulfate reduction to H2S, the relationship between sulfate-reducing bacteria activity and H2S yield, and real-time detection of sulfate-reducing bacteria activity using fluorescence sensors are described. The current challenges, such as low sensitivity and poor stability, are discussed.

Graphical abstract: Fluorescence chemosensors for hydrogen sulfide detection in biological systems

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Publication details

The article was received on 20 Oct 2014, accepted on 09 Dec 2014 and first published on 10 Dec 2014


Article type: Critical Review
DOI: 10.1039/C4AN01909A
Citation: Analyst, 2015,140, 1772-1786
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    Fluorescence chemosensors for hydrogen sulfide detection in biological systems

    Z. Guo, G. Chen, G. Zeng, Z. Li, A. Chen, J. Wang and L. Jiang, Analyst, 2015, 140, 1772
    DOI: 10.1039/C4AN01909A

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