Issue 6, 2013
From the journal:

Lab on a Chip

Raman-on-chip device and detection fibres with fibre Bragg grating for analysis of solutions and particles

Sebastian Dochow,a   Martin Becker,a   Ron Spittel,a   Claudia Beleites,a   Sarmiza Stanca,a   Ines Latka,a   Kay Schuster,a   Jens Kobelke,a   Sonja Unger,a   Thomas Henkel,a   Günter Mayer,a   Jens Albert,a   Manfred Rothhardt,a   Christoph Kraffta  and  Jürgen Popp*ab  

* Corresponding authors

a Institute of Photonic Technology (IPHT), Albert Einstein Straße 9, 07745 Jena, Germany
E-mail: juergen.popp@ipht-jena.de
Fax: +49-3641-206399
Tel: +49-3641-206300

b Institute of Physical Chemistry and Abbe Center of Photonics, University Jena, Helmholtzweg 4, 07743 Jena, Germany

Abstract

An all-fibre based Raman-on-chip setup is introduced which enables analysis of solutions and trapped particles without microscopes or objectives. Beside the novel quartz microfluidic chip, innovative multi-core single-mode fibres with integrated fibre Bragg gratings are used for detection. The limit of quantitation is 7.5 mM for urea and 2.5 mM for nicotine with linear Raman spectroscopy. This is an improvement of more than two orders of magnitude compared with previous fibre-based microfluidic Raman detection schemes. Furthermore, our device was combined with optical traps to collect Raman-on-chip spectra of spherical polymer beads.

Graphical abstract: Raman-on-chip device and detection fibres with fibre Bragg grating for analysis of solutions and particles

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Article information

DOI
https://doi.org/10.1039/C2LC41169E
Article type
Paper
Submitted
19 Oct 2012
Accepted
28 Nov 2012
First published
29 Nov 2012

Lab Chip, 2013,13, 1109-1113

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Raman-on-chip device and detection fibres with fibre Bragg grating for analysis of solutions and particles

S. Dochow, M. Becker, R. Spittel, C. Beleites, S. Stanca, I. Latka, K. Schuster, J. Kobelke, S. Unger, T. Henkel, G. Mayer, J. Albert, M. Rothhardt, C. Krafft and J. Popp, Lab Chip, 2013, 13, 1109 DOI: 10.1039/C2LC41169E

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