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Issue 1, 2012
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Ferrofluid mediated nanocytometry

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Abstract

We present a low-cost, flow-through nanocytometer that utilizes a colloidal suspension of non-functionalized magnetic nanoparticles for label-free manipulation and separation of microparticles. Our size-based separation is mediated by angular momentum transfer from magnetically excited ferrofluid particles to microparticles. The nanocytometer is capable of rapidly sorting and focusing two or more species, with up to 99% separation efficiency and a throughput of 3 × 104 particles/s per mm2 of channel cross-section. The device is readily scalable and applicable to live cell sorting with biocompatible ferrofluids, offering competitive cytometer performance in a simple and inexpensive package.

Graphical abstract: Ferrofluid mediated nanocytometry

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Publication details

The article was received on 10 Sep 2011, accepted on 20 Oct 2011 and first published on 11 Nov 2011


Article type: Paper
DOI: 10.1039/C1LC20864K
Citation: Lab Chip, 2012,12, 190-196
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    Ferrofluid mediated nanocytometry

    A. R. Kose and H. Koser, Lab Chip, 2012, 12, 190
    DOI: 10.1039/C1LC20864K

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