Jump to main content
Jump to site search
Publishing
Advanced

Issue 1, 2012
Previous Article Next Article

Ferrofluid mediated nanocytometry

Ayse Rezzan Kosea  and  Hur Koser*b 
Author affiliations

* Corresponding authors

a School of Engineering and Applied Science, Yale University, 15 Prospect St., Becton Center, Room 608, New Haven, USA
E-mail: ayse.kose@yale.edu
Fax: +1 (203) 432-6420
Tel: +1 (203) 432-8573

b School of Engineering and Applied Science, Yale University, 15 Prospect St., Becton Center, Room 507, New Haven, USA
E-mail: hur.koser@yale.edu
Fax: +1 (203) 432-6420
Tel: +1 (203) 432-9629

Abstract

We present a low-cost, flow-through nanocytometer that utilizes a colloidal suspension of non-functionalized magnetic nanoparticles for label-free manipulation and separation of microparticles. Our size-based separation is mediated by angular momentum transfer from magnetically excited ferrofluid particles to microparticles. The nanocytometer is capable of rapidly sorting and focusing two or more species, with up to 99% separation efficiency and a throughput of 3 × 104 particles/s per mm2 of channel cross-section. The device is readily scalable and applicable to live cell sorting with biocompatible ferrofluids, offering competitive cytometer performance in a simple and inexpensive package.

Graphical abstract: Ferrofluid mediated nanocytometry

Back to tab navigation
Download options Please wait...

Supplementary files

Publication details

The article was received on 10 Sep 2011, accepted on 20 Oct 2011 and first published on 11 Nov 2011


Article type: Paper
DOI: 10.1039/C1LC20864K
Citation: Lab Chip, 2012,12, 190-196
  •   Request permissions

    Ferrofluid mediated nanocytometry

    A. R. Kose and H. Koser, Lab Chip, 2012, 12, 190
    DOI: 10.1039/C1LC20864K

    If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using RightsLink. Go to our Instructions for using RightsLink page for details.

    Authors contributing to RSC publications (journal articles, books or book chapters) do not need to formally request permission to reproduce material contained in this article provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      Reproduced from Ref. XX with permission from the Centre National de la Recherche Scientifique (CNRS) and The Royal Society of Chemistry.
    • For reproduction of material from PCCP:
      Reproduced from Ref. XX with permission from the PCCP Owner Societies.
    • For reproduction of material from PPS:
      Reproduced from Ref. XX with permission from the European Society for Photobiology, the European Photochemistry Association, and The Royal Society of Chemistry.
    • For reproduction of material from all other RSC journals and books:
      Reproduced from Ref. XX with permission from The Royal Society of Chemistry.

    If the material has been adapted instead of reproduced from the original RSC publication "Reproduced from" can be substituted with "Adapted from".

    In all cases the Ref. XX is the XXth reference in the list of references.

    If you are the author of this article you do not need to formally request permission to reproduce figures, diagrams etc. contained in this article in third party publications or in a thesis or dissertation provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Reproduced by permission of The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC
    • For reproduction of material from PCCP:
      [Original citation] - Reproduced by permission of the PCCP Owner Societies
    • For reproduction of material from PPS:
      [Original citation] - Reproduced by permission of The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC
    • For reproduction of material from all other RSC journals:
      [Original citation] - Reproduced by permission of The Royal Society of Chemistry

    If you are the author of this article you still need to obtain permission to reproduce the whole article in a third party publication with the exception of reproduction of the whole article in a thesis or dissertation.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements