Jump to main content
Jump to site search

Issue 1, 2012
Previous Article Next Article

Isolation of prostate tumor initiating cells (TICs) through their dielectrophoretic signature

Author affiliations

Abstract

In this study, the dielectrophoretic response of prostate tumor initiating cells (TICs) was investigated in a microfluidic system utilizing contactless dielectrophoresis (cDEP). The dielectrophoretic response of prostate TICs was observed to be distinctively different than that for non-TICs, enabling them to be sorted using cDEP. Culturing the sorted TICs generated spheroids, indicating that they were indeed initiating cells. This study presents the first marker-free TIC separation from non-TICs utilizing their electrical fingerprints through dielectrophoresis.

Graphical abstract: Isolation of prostate tumor initiating cells (TICs) through their dielectrophoretic signature

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 29 Jul 2011, accepted on 20 Oct 2011 and first published on 09 Nov 2011


Article type: Paper
DOI: 10.1039/C1LC20701F
Citation: Lab Chip, 2012,12, 182-189
  •   Request permissions

    Isolation of prostate tumor initiating cells (TICs) through their dielectrophoretic signature

    A. Salmanzadeh, L. Romero, H. Shafiee, R. C. Gallo-Villanueva, M. A. Stremler, S. D. Cramer and R. V. Davalos, Lab Chip, 2012, 12, 182
    DOI: 10.1039/C1LC20701F

Search articles by author