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Issue 43, 2012
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Ionic liquids promote PCR amplification of DNA

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Abstract

A bicyclic imidazolium ionic liquid (4d), [b-4C-im][Br], was found to be highly effective not only for promoting PCR of GC-rich DNA by minimizing non-specific amplification, but also for facilitating PCR of normal-GC DNA under mild conditions.

Graphical abstract: Ionic liquids promote PCR amplification of DNA

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Publication details

The article was received on 08 Mar 2012, accepted on 05 Apr 2012 and first published on 10 Apr 2012


Article type: Communication
DOI: 10.1039/C2CC31740K
Citation: Chem. Commun., 2012,48, 5325-5327
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    Ionic liquids promote PCR amplification of DNA

    Y. Shi, Y. Liu, P. Lai, M. Tseng, M. Tseng, Y. Li and Y. Chu, Chem. Commun., 2012, 48, 5325
    DOI: 10.1039/C2CC31740K

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