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Issue 4, 2012
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The reverse of polymer degradation: in situ crosslinked gel formation through disulfide cleavage

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Abstract

In contrast to the usual inclusion of disulfide bonds within a polymer structure to facilitate bio-degradation, we have designed a self-curing “one pot” hyperbranched polymer capable of forming crosslinked gels under reducing conditions abundant in tumoural tissue.

Graphical abstract: The reverse of polymer degradation: in situ crosslinked gel formation through disulfide cleavage

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Publication details

The article was received on 20 Oct 2011, accepted on 10 Nov 2011 and first published on 11 Nov 2011


Article type: Communication
DOI: 10.1039/C1CC16538K
Citation: Chem. Commun., 2012,48, 585-587
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    The reverse of polymer degradation: in situ crosslinked gel formation through disulfide cleavage

    A. O. Saeed, B. Newland, A. Pandit and W. Wang, Chem. Commun., 2012, 48, 585
    DOI: 10.1039/C1CC16538K

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