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Issue 11, 2012
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Logic gates for multiplexed analysis of Hg2+ and Ag+

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The design of devices with multiple functions, simple handling procedures and sufficient sensitivity has drawn great interests in the field of analysis. Metal–nucleotide based pairs, such as T–Hg2+–T and C–Ag+–C complexes accompanied by SYBR Green I (SG), are used to selectively bind duplex-strand DNA by observing a bright fluorescence signal in this work, thus yielding a simple method for the rapid detection of Hg2+ and Ag+ without a complex labeling process. Based on this principle, ‘OR’ and ‘AND’ logic gates for the multiplexed analysis of Hg2+ and Ag+ were developed, and their practical application for the detection of Hg2+ and Ag+ in drinking water was reported.

Graphical abstract: Logic gates for multiplexed analysis of Hg2+ and Ag+

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Publication details

The article was received on 08 Feb 2012, accepted on 13 Mar 2012 and first published on 14 Mar 2012

Article type: Paper
DOI: 10.1039/C2AN35180C
Citation: Analyst, 2012,137, 2687-2691
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    Logic gates for multiplexed analysis of Hg2+ and Ag+

    G. Zhang, W. Lin, W. Yang, Z. Lin, L. Guo, B. Qiu and G. Chen, Analyst, 2012, 137, 2687
    DOI: 10.1039/C2AN35180C

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