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Issue 2, 2011
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Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

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Abstract

A continuous-flow palladium-catalyzed amination reaction was made possible through efficient handling of solids via acoustic irradiation. Various diarylamines were obtained with reaction times ranging from 20 s to 10 min.

Graphical abstract: Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

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Publication details

The article was received on 16 Oct 2010, accepted on 18 Nov 2010 and first published on 03 Dec 2010


Article type: Edge Article
DOI: 10.1039/C0SC00524J
Citation: Chem. Sci., 2011,2, 287-290
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    Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

    T. Noël, J. R. Naber, R. L. Hartman, J. P. McMullen, K. F. Jensen and S. L. Buchwald, Chem. Sci., 2011, 2, 287
    DOI: 10.1039/C0SC00524J

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