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Issue 2, 2010
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Counting single molecules in sub-nanolitre droplets

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Abstract

We demonstrate single biomolecule detection and quantification within sub-nanolitre droplets through application of Cylindrical Illumination Confocal Spectroscopy (CICS) and droplet confinement within a retractable microfluidic constriction.

Graphical abstract: Counting single molecules in sub-nanolitre droplets

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Publication details

The article was received on 26 Aug 2009, accepted on 02 Oct 2009 and first published on 09 Oct 2009


Article type: Communication
DOI: 10.1039/B917503B
Citation: Lab Chip, 2010,10, 161-164
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    Counting single molecules in sub-nanolitre droplets

    T. D. Rane, C. M. Puleo, K. J. Liu, Y. Zhang, A. P. Lee and T. H. Wang, Lab Chip, 2010, 10, 161
    DOI: 10.1039/B917503B

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