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Paper

A microfluidics-based turning assay reveals complex growth cone responses to integrated gradients of substrate-bound ECM molecules and diffusible guidance cues

C. Joanne Wang,ac   Xiong Li,ac   Benjamin Lin,a   Sangwoo Shim,bc   Guo-li Mingbc and   Andre Levchenko*ac  
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a
Department of Biomedical Engineering and Whitaker Institute of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, USA
b
Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, USA
c
Institute of Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, USA
E-mail: alev@jhu.edu;
Fax: +1 410 516 6240 ;
Tel: +1 410 516 6241
Lab Chip, 2008,8, 227-237

DOI: 10.1039/B713945D
Received 11 Sep 2007, Accepted 04 Dec 2007
First published online 04 Jan 2008
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