Microcontact printing of proteins for neuronal cell guidance

Andreas Offenhäusser; Simone Böcker-Meffert; Tanja Decker; Rita Helpenstein; Peter Gasteier; Jürgen Groll; Martin Möller; Anna Reska; Susanne Schäfer; Petra Schulte; Angela Vogt-Eisele

doi:10.1039/B607615G

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Soft Matter

Issue 3, 2007

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Microcontact printing of proteins for neuronal cell guidance

Andreas Offenhäusser , Simone Böcker-Meffert , Tanja Decker , Rita Helpenstein , Peter Gasteier , Jürgen Groll , Martin Möller , Anna Reska , Susanne Schäfer , Petra Schulte and Angela Vogt-Eisele

Soft Matter, 2007, 3, 290-298

DOI: 10.1039/B607615G
Received 30 May 2006, Accepted 10 Jan 2007
First published on the web 02 Feb 2007
This article is part of the collection: Cells and proteins at interfaces

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The growth of neurons into networks of controlled geometry is of great interest in the field of cell-based biosensors, neuroelectronic circuits, neurological implants, pharmaceutical testing as well as fundamental biological questions about neuronal interactions. The precise control of the network architecture can be achieved by defined engineering of the surface material properties: this process is called neuronal cell patterning. Different techniques can be used to produce such surface patterns. We have chosen microcontact printing (μCP), because it is a comparatively simple and universal method for patterning biomolecules.

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Soft Matter

Microcontact printing of proteins for neuronal cell guidance

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