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Issue 48, 2006
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Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe

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Abstract

A novel anthracene-tagged oligonucleotide can discriminate between a fully-matched DNA target sequence and one with a single mismatching base-pair through a remarkable difference in fluorescence emission intensity upon duplex formation.

Graphical abstract: Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe

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Publication details

The article was received on 14 Aug 2006, accepted on 23 Oct 2006 and first published on 06 Nov 2006


Article type: Communication
DOI: 10.1039/B611650G
Citation: Chem. Commun., 2006,0, 5003-5005
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    Detection of a single DNA base-pair mismatch using an anthracene-tagged fluorescent probe

    N. Moran, D. M. Bassani, J. Desvergne, S. Keiper, P. A. S. Lowden, J. S. Vyle and J. H. R. Tucker, Chem. Commun., 2006, 0, 5003
    DOI: 10.1039/B611650G

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