This review aims to collect advancements in enantioselective palladium-catalyzed cyclization reactions over the past eleven years, and it is organized into thirteen sections depending on the different types of transformations involved.
The aza-Friedel–Crafts (aza-FC) reaction is a very powerful tool for forming C–C and C–N bonds, based on an acid-catalyzed addition of electron-rich aromatic compounds to imines.
We report a chiral phosphoric acid-catalyzed asymmetric aza-Friedel–Crafts reaction of newly developed indeno[1,2-b]quinoxalin-11-imines for the efficient synthesis of diverse chiral 11-amino-indeno[1,2-b]quinoxaline derivatives.
A class of novel pyrrolinone ketimines was synthesized for the first time and applied to the asymmetric aza-Friedel–Crafts reaction with phenolic compounds.
An Ru-catalyzed carbamoyl-directed C–H functionalization of indoles and indolines with 7-azabenzonorbornadienes results in 2-aminodihydronaphthyl indoles and 7-aminodihydronaphthyl indolines, respectively.