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Automated optimization under dynamic flow conditions

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Autonomous model-based experimental design for rapid reaction development

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Accelerating reaction optimization through data-rich experimentation and machine-assisted process development

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Automated self-optimization of continuous crystallization of nirmatrelvir API

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Extrapolation performance improvement by quantum chemical calculations for machine-learning-based predictions of flow-synthesized binary copolymers

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A Chemist's guide to multi-objective optimization solvers for reaction optimization

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Heterogeneous photochemical reaction enabled by an ultrasonic microreactor

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Multiphase photochemistry in flow mode via an integrated continuous stirred tank reactor (CSTR) approach

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Continuous synthesis of block copolymer nanoparticlesviatelescoped RAFT solution and dispersion polymerisation in a miniature CSTR cascade

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Use of open-source software platform to develop dashboards for control and automation of flow chemistry equipment

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Digital Discovery, 2022, 1, 596
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Adaptive mixed variable Bayesian self-optimisation of catalytic reactions

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Microreactor-based micro/nanomaterials: fabrication, advances, and outlook

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Self-optimising continuous-flow hydrothermal reactor for nanoparticle synthesis

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Microfluidic platform for screening the activity of immobilized photocatalysts for degradation of water pollutants in flow

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A field guide to flow chemistry for synthetic organic chemists

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Chem. Sci., 2023, 14, 4230
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Bayesian data-driven models for pharmaceutical process development

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Nonclogging Liquid-Walled Continuous Flow Reactors

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AI for organic and polymer synthesis

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Multiphasic Continuous‐Flow Reactors for Handling Gaseous Reagents in Organic Synthesis: Enhancing Efficiency and Safety in Chemical Processes

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Angewandte Chemie, 2024, 136
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Bayesian Self‐Optimization for Telescoped Continuous Flow Synthesis

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Modular Cascade of Flow Reactors: Continuous Flow Synthesis of Water‐Insoluble Diazo Dyes in Aqueous System

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ChemSusChem, 2024
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Early-Stage Flow Process Development of a Key Intermediate toward PF-07265807, an AXL-MER Inhibitor Oncology Candidate

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Initial Sample Selection in Bayesian Optimization for Combinatorial Optimization of Chemical Compounds

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ACS Omega, 2023, 8, 2001
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Bayesian optimization of radical polymerization reactions in a flow synthesis system

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Bayesian Optimization for Chemical Synthesis in the Era of Artificial Intelligence: Advances and Applications

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Continuously Stirred Tank Reactor for Pharmaceutical and Chemical Applications

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Recent Developments in Reactor Automation for Multistep Chemical Synthesis

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A Review of the Applications of Artificial Intelligence in the Process Analysis and Optimization of Chemical Products

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Bayesian Optimization of Operating Points of a Continuous Perhydro‐Dibenzyltoluene Dehydrogenation Reactor

Alexander Verhoolen, Michael Geißelbrecht, Julian Kadar, Patrick Preuster, Peter Wasserscheid, Knut Graichen and Zhien Zhang

International Journal of Energy Research, 2024, 2024
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Bayesian Optimization as a Sustainable Strategy for Early-Stage Process Development? A Case Study of Cu-Catalyzed C–N Coupling of Sterically Hindered Pyrazines

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ACS Sustainable Chem. Eng., 2023, 11, 10545
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A Review on Artificial Intelligence Enabled Design, Synthesis, and Process Optimization of Chemical Products for Industry 4.0

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Self-Driving Laboratories for Chemistry and Materials Science

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Bayesian Self‐Optimization for Telescoped Continuous Flow Synthesis

Adam D. Clayton, Edward O. Pyzer‐Knapp, Mark Purdie, Martin F. Jones, Alexandre Barthelme, John Pavey, Nikil Kapur, Thomas W. Chamberlain, A. John Blacker and Richard A. Bourne

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Emerging trends in the optimization of organic synthesis through high-throughput tools and machine learning

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Multiphasic Continuous‐Flow Reactors for Handling Gaseous Reagents in Organic Synthesis: Enhancing Efficiency and Safety in Chemical Processes

Annechien A. H. Laporte, Tom M. Masson, Stefan D. A. Zondag and Timothy Noël

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