Divergent synthesis of multi-substituted phenanthrenes via an internal redox reaction/ring expansion sequence

Ryosei Koyama, Masahiro Anada, Shunsuke Sueki, Kosho Makino, Tatsuhiro Kojima, Tomoko Kawasaki-Takasuka and Keiji Mori

Chem. Commun., 2024, 60, 3822
DOI: 10.1039/D4CC00797B

Organic photoredox catalyzed C(sp3)–H functionalization of saturated aza-heterocycles via a cross-dehydrogenative coupling reaction

Yi-Fan Zhang, Han-Nan Chen, Yi Xiao, Zhencun Cui, Wei David Wang and Guo-Qiang Xu

Org. Biomol. Chem., 2023, 21, 8284
DOI: 10.1039/D3OB01438J

Stereoselective synthesis of 6/7/6-fused heterocycles with multiple stereocenters via an internal redox reaction/inverse electron-demand hetero-Diels–Alder reaction sequence

Dan Sakai, Tatsuhiro Kojima, Tomoko Kawasaki-Takasuka and Keiji Mori

Chem. Commun., 2024, 60, 6797
DOI: 10.1039/D4CC02351J

Alkyl amines and ethers as traceless hydride donors in [1,5]-hydride transfer cascade reactions

Yao-Bin Shen, Fangzhi Hu and Shuai-Shuai Li

Org. Biomol. Chem., 2023, 21, 700
DOI: 10.1039/D2OB02146C

Green and modular synthesis of azepino[4,3,2-cd]indoles and diazepino[6,5,4-cd]indoles via hydride transfer-involved cascade cyclization in ethanol

Qian-Hao Zhuang, Xiao-Lin Wang, Wei Gao, Bin Qiu, Xiao-De An, Houchen Wang, Yao-Bin Shen and Jian Xiao

Org. Chem. Front., 2025, 12, 4808
DOI: 10.1039/D5QO00058K

Water-enabled α-C(sp3)–H amination via [1,6]-hydride transfer: green access to diazepino[6,5,4-cd]indoles

Yao-Bin Shen, Xiao-Lin Wang, Qian-Hao Zhuang, Xiao-De An, Bin Qiu, Houchen Wang, Tiesheng Shi and Jian Xiao

Org. Chem. Front., 2025, 12, 591
DOI: 10.1039/D4QO01761G

Cascade dearomative [4 + 2] cycloaddition of indoles with in situ generated ortho-quinone methides: practical access to divergent indoline-fused polycycles

Pei-Zhen Dong, Bin Qiu, Xiao-De An and Jian Xiao

Green Chem., 2022, 24, 3772
DOI: 10.1039/D2GC00387B

B(C6F5)3-catalyzed stepwise 1,5-hydride migration/cyclization: diastereoselective construction of carbocyclic β-amino acid derivatives

Zhiting Wang, Hongchi Liu, Tianxiao Jiang and Hanmin Huang

Org. Chem. Front., 2024, 11, 864
DOI: 10.1039/D3QO01637D

EtOH-mediated cascade C(sp3)–H alkylation via aromatization-driven [1,6]-hydride transfer: green and divergent synthesis of spirocyclic azepino[4,3,2-cd]indoles

Yao-Bin Shen, Qian-Hao Zhuang, Xiao-Lin Wang, Xiao-De An, Bin Qiu, Tiesheng Shi and Jian Xiao

Green Chem., 2024, 26, 11899
DOI: 10.1039/D4GC04534C

Synthesis of biologically active [1,5]diazocino[2,1-b]quinazolinones through [4 + 4] cycloaddition of 2-alkynyl quinazolinones with aza-ortho-quinone methides

Li Pang, Shu-Jun Fang, Pei-Sen Zou, Wang Wang, Jun-Cheng Su, Xiao-Qing Liu, Cheng-Xue Pan, Dong-Liang Mo and Gui-Fa Su

Org. Chem. Front., 2023, 10, 1780
DOI: 10.1039/D3QO00056G

Photocatalyst- and transition-metal-free syntheses of furan-fused dihydroazepines by visible light

Babasaheb Sopan Gore, Chiao-Ying Kuo and Jeh-Jeng Wang

Green Chem., 2023, 25, 8074
DOI: 10.1039/D3GC02364H

B(C6F5)3-Catalyzed α,β-Difunctionalization and C–N Bond Cleavage of Saturated Amines with Benzo[c]isoxazoles: Access to Quinoline Derivatives

Yan He, Qimeng Liu, Zihe Du, Yanhua Xu, Lingyu Cao, Xinying Zhang and Xuesen Fan

J. Org. Chem., 2022, 87, 14840
DOI: 10.1021/acs.joc.2c01290

Rapid access to phenanthrene-based fused lactones via C(sp3)–H bond functionalization initiated triple ring construction

Ryosei Koyama, Takayuki Matsuno, Masahiro Anada, Shunsuke Sueki, Kosho Makino, Tomoko Kawasaki-Takasuka and Keiji Mori

Tetrahedron Chem, 2025, 15, 100138
DOI: 10.1016/j.tchem.2025.100138

Diastereoselective Bidirectional C(sp3)−H Bond Functionalization of Piperazine Compounds

Xiao‐Le Zhou, Chi‐Tung Yeung, Wesley Ting Kwok Chan and Ga‐Lai Law

Adv Synth Catal, 2022, 364, 732
DOI: 10.1002/adsc.202101187

TFE-Facilitated Synthesis of Tetrahydropyridino[2,3-d]pyrimidine via Cascade [1,5]-Hydride Transfer/Cyclization

Cong Wei, Yan Li, Xin Yao, Kui Zhang and Lingchao Cai

J. Org. Chem., 2023, 88, 17144
DOI: 10.1021/acs.joc.3c02004

Gold-Catalyzed Intermolecular Assembly of Donor and Acceptor Fragments for [1,5]-Hydride Migrations

Xiao-Qian Zhang, Ningbo Li, Yongliang Zhang and Youliang Wang

Org. Lett., 2025, 27, 3426
DOI: 10.1021/acs.orglett.5c00816

Hydride Shift Mediated C(sp³)-H Bond Functionalization(Internal Redox Reaction)

Keiji Mori and Takahiko Akiyama

J. Synth. Org. Chem. Jpn., 2023, 81, 582
DOI: 10.5059/yukigoseikyokaishi.81.582

Access to polycyclic diazepino[5,6,7-cd]indoles from isatins via tandem 1,5-hydride transfer/cyclization

Zhonglin Wang, Longfei Li, Bin Qiu, Xiao-De An and Jian Xiao

Tetrahedron Letters, 2023, 122, 154518
DOI: 10.1016/j.tetlet.2023.154518

The crystal structure of [1-(4-(trifluoromethyl)phenyl)-3,4-dihydroquinolin-2(1H)-one], C16H12F3NO

Xuewei Pu, Fanjie Meng and Shaoliang Zhang

Zeitschrift für Kristallographie - New Crystal Structures, 2023, 238, 857
DOI: 10.1515/ncrs-2023-0240

Quinoline as an Intramolecular Hydride Shuttle in the Deoxygenative Coupling Reaction of Alcohol and the Inert Methyl C(sp3)–H Bond

Hui-Yun Wang, Zhen-Yuan Liu, Long-Xue Wang, Da-Ying Shao, Feng-Ying Dong, Yao-Bin Shen, Bin Qiu, Jian Xiao and Xiao-De An

J. Org. Chem., 2024, 89, 18406
DOI: 10.1021/acs.joc.4c02269

Chemodivergent Spirocyclization of 2‐Sec‐Aminobenzilidene Imidazolones: Lewis Versus Brønsted Acids Catalysis

Dmitrii S. Ivanov, Elvira R. Zaitseva, Alexander Yu. Smirnov, Dina A. Rustamova, Andrey A. Mikhaylov, Maria A. Sycheva, Darya A. Gluschenko, Nadezhda S. Baleeva and Mikhail S. Baranov

Adv Synth Catal, 2022, 364, 1587
DOI: 10.1002/adsc.202200109

Synthesis of Quinazolinone-Fused Tetrahydroisoquinolines and Related Polycyclic Scaffolds by Iodine-Mediated sp3 C–H Amination

Manman Wang, Wenjun Ye, Nannan Sun, Wenquan Yu and Junbiao Chang

J. Org. Chem., 2023, 88, 1061
DOI: 10.1021/acs.joc.2c02509

(n+3)-Cyclization for the Formation of Benzo[7]annulene Derivatives via a [1,4]-Hydride Shift: A Novel Cyclization Mode Involving an Internal Redox Reaction

Jun Nagaki, Tomoko Kawasaki-Takasuka and Keiji Mori

Synlett, 2024, 35, 2143
DOI: 10.1055/a-2287-9391

Hydride Transfer-Initiated Cross-Dehydrogenative Coupling Reaction to Access Nine-Membered Rings

Xiao-De An, Da-Ying Shao, Bin Qiu and Jian Xiao

Org. Lett., 2023, 25, 2432
DOI: 10.1021/acs.orglett.3c00193

Divergent synthesis of new naphtho-fused 2-aminoindolines and naphthoxindoles based on straightforward construction of phenanthrene

Bin Qiu, Ya-Fei Shi, Xiao-De An, Shu-Kui Guo, Yao-Bin Shen and Jian Xiao

Green Synthesis and Catalysis, 2025, 6, 110
DOI: 10.1016/j.gresc.2023.11.001

Strategies Employing Transition‐Metal Free Conditions for C−C Bond Formation in Indoles

Balaji M. Ghodake, Sayantan Paul and Asish K. Bhattacharya

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202403280

1,7-Hydride transfer-involved dearomatization of quinolines to access C3-spiro hydroquinolines

Da-Ying Shao, Bin Qiu, Zi-Kang Wang, Zhen-Yuan Liu, Jian Xiao and Xiao-De An

Green Synthesis and Catalysis, 2025, 6, 123
DOI: 10.1016/j.gresc.2024.01.008

Divergent Access to Seven/Five-Membered Rings Based on [1,6]-Hydride Shift/Cyclization Process

Daiki Hoshino and Keiji Mori

Org. Lett., 2021, 23, 9403
DOI: 10.1021/acs.orglett.1c03523

The Cascade [1,5]-Hydride Shift/Intramolecular C(sp3)–H Activation: A Powerful Approach to the Construction of Spiro-Tetrahydroquinoline Skeleton

Hongmei Liu, Yunyun Quan, Long Xie, Xiang Li and Xin Xie

Front. Chem., 2022, 10
DOI: 10.3389/fchem.2022.840934

Sustainable Synthesis of Medicinally Important Heterocycles

Dripta De Joarder, Rajarshi Sarkar and Dilip K. Maiti

MRMC, 2025, 25, 760
DOI: 10.2174/0113895575341409241201171848

Synthesis of All Ring Sizes of Medium-Sized Heterocycles Bridged Biaryls via VQM-Enabled Diversity-Oriented Synthetic Strategy

Shu-Kui Guo, Yu-Han Zhang, Fan Yang, Xiao-De An, Yao-Bin Shen, Jian Xiao and Bin Qiu

Org. Lett., 2025, 27, 3237
DOI: 10.1021/acs.orglett.5c00531

Direct Access to 9/6‐Fused Cycles via Sequential Hydride Shift Mediated Double C(sp3)−H Bond Functionalization

Issei Nakamura, Masahiro Anada, Shunsuke Sueki, Kosho Makino and Keiji Mori

Adv Synth Catal, 2023, 365, 502
DOI: 10.1002/adsc.202201354

1,6-Hydride Transfer-Enabled [6 + 1] Annulation to Access Polycyclic 3,4-Fused Azepinoindoles

Xiao-De An, Zhonglin Wang, Yao-Bin Shen, Bin Qiu and Jian Xiao

J. Org. Chem., 2023, 88, 8791
DOI: 10.1021/acs.joc.3c00631