Exosomal miR-205–5p contributes to the immune liver injury induced by trichloroethylene: Pivotal role of RORα mediating M1 Kupffer cell polarization

Hui Wang, Feng Wang, Yu Li, Pengcheng Zhou, Shuyang Cai, Qifeng Wu, Tao Ding, Changhao Wu and Qixing Zhu

Ecotoxicology and Environmental Safety, 2024, 285, 117050
DOI: 10.1016/j.ecoenv.2024.117050

Evaluating impacts of the trichloroethylene metabolite S -(1,2-dichlorovyinyl)-L-cysteine on transcriptomic responses and cytokine release in a macrophage model: implications for pregnancy outcomes

Annella Benjamin, Erica Boldenow, Sammy Jaber, Kelly Bakulski, John Dou, Justin Colacino, Peter Mancuso and Sean Harris

Journal of Immunotoxicology, 2025, 22
DOI: 10.1080/1547691X.2025.2522041

Transcriptional profiling of the response to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine revealed activation of the eIF2α/ATF4 integrated stress response in two in vitro placental models

Elana R. Elkin, Kelly M. Bakulski, Justin A. Colacino, Dave Bridges, Brian A. Kilburn, D. Randall Armant and Rita Loch-Caruso

Arch Toxicol, 2021, 95, 1595
DOI: 10.1007/s00204-021-03011-5

Unlocking the secrets: Volatile Organic Compounds (VOCs) and their devastating effects on lung cancer

Md Sadique Hussain, Gaurav Gupta, Riya Mishra, Neeraj Patel, Saurabh Gupta, Sami I. Alzarea, Imran Kazmi, Popat Kumbhar, John Disouza, Harish Dureja, Neelima Kukreti, Sachin Kumar Singh and Kamal Dua

Pathology - Research and Practice, 2024, 255, 155157
DOI: 10.1016/j.prp.2024.155157

Sexually concordant and dimorphic transcriptional responses to maternal trichloroethylene and/or N-acetyl cysteine exposure in Wistar rat placental tissue

Elana R. Elkin, Anthony L. Su, John F. Dou, Justin A. Colacino, Dave Bridges, Vasantha Padmanabhan, Sean M. Harris, Erica Boldenow, Rita Loch-Caruso and Kelly M. Bakulski

Toxicology, 2023, 483, 153371
DOI: 10.1016/j.tox.2022.153371

Maternal occupational exposure to organic solvents and intrauterine growth in the ELFE cohort

Isabelle Enderle, Virginie De Lauzun, Marie Astrid Metten, Marion Monperrus, Fleur Delva, Pauline Blanc-Petitjean, Brigitte Dananche, Christophe Paris, Cécile Zaros, Maela Le Lous, Rémi Béranger and Ronan Garlantézec

Environmental Research, 2023, 224, 115187
DOI: 10.1016/j.envres.2022.115187

Biochar-based composites for removing chlorinated organic pollutants: Applications, mechanisms, and perspectives

Qingqing Song, Fanying Kong, Bing-Feng Liu, Xueting Song and Hong-Yu Ren

Environmental Science and Ecotechnology, 2024, 21, 100420
DOI: 10.1016/j.ese.2024.100420

Utilizing machine learning algorithm for finely three-dimensional delineation of soil-groundwater contamination in a typical industrial park, North China: Importance of multisource auxiliary data

Siyan Liu, Xiao Yang, Biling Shi, Zhaoshu Liu, Xiulan Yan, Yaoyu Zhou and Tao Liang

Science of The Total Environment, 2024, 911, 168598
DOI: 10.1016/j.scitotenv.2023.168598

Environmental chemicals and adverse pregnancy outcomes: Placenta as a target and possible driver of pre- and postnatal effects

Jing Li, Adrian Covaci and Da Chen

Critical Reviews in Environmental Science and Technology, 2023, 53, 964
DOI: 10.1080/10643389.2022.2104075

The effect of Ipomoea carnea on maternal reproductive outcomes and fetal and postnatal development in rats

André Tadeu Gotardo, Luciana Lucinio Lippi, Kalan Bastos Violin, Estela Maris Andrade Forell Bevilacqua and Silvana Lima Górniak

Toxicon, 2021, 190, 3
DOI: 10.1016/j.toxicon.2020.11.012

Trichloroethylene: An Invisible Cause of Parkinson’s Disease?

E. Ray Dorsey, Maryam Zafar, Samantha E. Lettenberger, Meghan E. Pawlik, Dan Kinel, Myrthe Frissen, Ruth B. Schneider, Karl Kieburtz, Caroline M. Tanner, Briana R. De Miranda, Samuel M. Goldman and Bastiaan R. Bloem

Journal of Parkinson’s Disease, 2023, 13, 203
DOI: 10.3233/JPD-225047

Exposure to cis- and trans-regioisomers of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-glutathione result in quantitatively and qualitatively different cellular effects in RPTEC/TERT1 cells

Liliana Capinha, Paul Jennings and Jan N.M. Commandeur

Toxicology Letters, 2023, 383, 75
DOI: 10.1016/j.toxlet.2023.06.005

Childhood cancer risk in offspring of mothers occupationally exposed to hydrocarbon solvents

Yixin Chen, Chuanjie Deng, Beate R. Ritz, Johnni Hansen, Zuo-Feng Zhang and Julia E. Heck

European Journal of Cancer Prevention, 2026, 35, 141
DOI: 10.1097/CEJ.0000000000000988

Photocatalytic Degradation of Trichloroethylene Under Different Environmental Conditions: Kinetics and Carbon Isotope Effects

Yufeng Wang, Yaqiong Dong, Lantian Xing, Yuanxiao Guan and Changjie Liu

Water, 2025, 17, 1533
DOI: 10.3390/w17101533

Toxicity assessments of selected trichloroethylene and perchloroethylene metabolites in three in vitro human placental models

Elana R. Elkin, Anthony L. Su, Brian A. Kilburn, Kelly M. Bakulski, D. Randall Armant and Rita Loch-Caruso

Reproductive Toxicology, 2022, 109, 109
DOI: 10.1016/j.reprotox.2022.03.003

Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry

Andrew Jordan, Patrick Stoy and Helen F. Sneddon

Chem. Rev., 2021, 121, 1582
DOI: 10.1021/acs.chemrev.0c00709

Trichloroethylene: An Update on an Environmental Contaminant with Multiple Health Effects

Lawrence H. Lash

Annual Review of Pharmacology and Toxicology, 2025, 65, 507
DOI: 10.1146/annurev-pharmtox-022724-120525

Trichloroethylene─A Review of Its Safety Concerns and Environmental Hazard Levels

Yasin Sarpeleh, Zahra Jamali and Masoud Khajenoori

ACS Chem. Health Saf., 2026
DOI: 10.1021/acs.chas.5c00145

Multiple maternal occupational exposures during pregnancy and intrauterine growth: analysis of the French Longitudinal Study of Children - ELFE cohort, using data-driven approaches

Marie Tartaglia, Calvin Ge, Anjoeka Pronk, Nathalie Costet, Sabyne Audignon-Durand, Marie-Tülin Houot, Katarina Kjellberg, Maxime Turuban, Nel Roeleveld, Jack Siemiatycki, Camille Carles, Corinne Pilorget, Daniel Falkstedt, Sanni Uuksulainen, Michelle C. Turner, Alexis Descatha, Marie Noëlle Dufourg, Fleur Delva and Ronan Garlantézec

International Journal of Hygiene and Environmental Health, 2025, 270, 114666
DOI: 10.1016/j.ijheh.2025.114666

Exposure to the trichloroethylene metabolite S-(1,2-dichlorovinyl)-L-cysteine under hypoxic conditions (%O2 =2 %) alters differential gene expression and mitigates decreased invasion capacity, compared to normoxic conditions (%O2 ≥ 21 %) in HTR-8/SVneo cells

Franny H. Stein, Nora H. Le and Elana R. Elkin

Toxicology Letters, 2025, 414, 111773
DOI: 10.1016/j.toxlet.2025.111773