Issue 10, 2018

Multicomponent peptide assemblies

Abstract

Self-assembled peptide nanostructures have been increasingly exploited as functional materials for applications in biomedicine and energy. The emergent properties of these nanomaterials determine the applications for which they can be exploited. It has recently been appreciated that nanomaterials composed of multicomponent coassembled peptides often display unique emergent properties that have the potential to dramatically expand the functional utility of peptide-based materials. This review presents recent efforts in the development of multicomponent peptide assemblies. The discussion includes multicomponent assemblies derived from short low molecular weight peptides, peptide amphiphiles, coiled coil peptides, collagen, and β-sheet peptides. The design, structure, emergent properties, and applications for these multicomponent assemblies are presented in order to illustrate the potential of these formulations as sophisticated next-generation bio-inspired materials.

Graphical abstract: Multicomponent peptide assemblies

Article information

Article type
Review Article
Submitted
07 Feb 2018
First published
26 Eph 2018

Chem. Soc. Rev., 2018,47, 3659-3720

Author version available

Multicomponent peptide assemblies

D. M. Raymond and B. L. Nilsson, Chem. Soc. Rev., 2018, 47, 3659 DOI: 10.1039/C8CS00115D

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