Issue 84, 2018
From the journal:

Chemical Communications

Fluorine-18: an untapped resource in inorganic chemistry

Cassis Varlow,†ab   Daniel Szames,†ab   Kenneth Dahl,ac   Vadim Bernard-Gauthierac  and  Neil Vasdev ORCID logo *ac  

* Corresponding authors

a Azrieli Centre for Neuro-Radiochemistry, Research Imaging Centre, Centre for Addiction and Mental Health, 250 College St. Toronto, ON, Canada
E-mail: neil.vasdev@utoronto.ca
Tel: +1-416-535-8501 ext. 30988

b Department of Chemistry and Chemical Biology, McMaster University, 1280 Main St. W., Hamilton, ON, Canada

c Department of Psychiatry, University of Toronto, 250 College St. Toronto, ON, Canada

Abstract

Advances in the field of fluorine chemistry have been applied extensively to the syntheses of 18F-labelled organic compounds and radiopharmaceuticals. However, 18F has sparely been used as a tool to explore inorganic chemistry and can be viewed as a research area worthy of further development. This review highlights the application of 18F in development of inorganic fluorinating agents, mechanistic studies and imaging tools.

Graphical abstract: Fluorine-18: an untapped resource in inorganic chemistry

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Article information

DOI
https://doi.org/10.1039/C8CC04751K
Article type
Highlight
Submitted
13 Jun 2018
Accepted
28 Aga 2018
First published
29 Aga 2018

Chem. Commun., 2018,54, 11835-11842

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Fluorine-18: an untapped resource in inorganic chemistry

C. Varlow, D. Szames, K. Dahl, V. Bernard-Gauthier and N. Vasdev, Chem. Commun., 2018, 54, 11835 DOI: 10.1039/C8CC04751K

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