Issue 10, 2020

Ethyl lactate-involved three-component dehydrogenative reactions: biomass feedstock in diversity-oriented quinoline synthesis

Abstract

Three-component reactions of ethyl/methyl lactate, anilines and aldehydes providing quinolines have been developed via simple iron(III) chloride catalysis without using an additional organic medium or external oxidant. This three-component protocol shows high efficiency and broad substrate tolerance, allowing quick access to diverse quinoline products under neat reaction conditions. The results reported herein disclose important new applications of green biomass feedstock in the clean synthesis of valuable organic products.

Graphical abstract: Ethyl lactate-involved three-component dehydrogenative reactions: biomass feedstock in diversity-oriented quinoline synthesis

Supplementary files

Article information

Article type
Communication
Submitted
01 Mas 2020
Accepted
30 Eph 2020
First published
30 Eph 2020

Green Chem., 2020,22, 3074-3078

Ethyl lactate-involved three-component dehydrogenative reactions: biomass feedstock in diversity-oriented quinoline synthesis

L. Yang and J. Wan, Green Chem., 2020, 22, 3074 DOI: 10.1039/D0GC00738B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements