Issue 29, 2019

The diiodomethyl-sulfonyl moiety: an unexplored halogen bond-donor motif

Abstract

Herein, we report the crystal structures of the antimicrobial agent diiodomethyl-p-tolylsulfone and of three halogen bonded co-crystals demonstrating that the bioactive moiety –SO2CHI2 can function as a quite effective halogen bond based motif in the solid state and in solution, namely demonstrating that α-iodosulfones may become a new entry in the quite small group of alkyl-iodides functioning as reliable halogen bond-donors.

Graphical abstract: The diiodomethyl-sulfonyl moiety: an unexplored halogen bond-donor motif

Supplementary files

Article information

Article type
Communication
Submitted
06 Feb 2019
Accepted
14 Mas 2019
First published
20 Mas 2019

Chem. Commun., 2019,55, 4234-4237

The diiodomethyl-sulfonyl moiety: an unexplored halogen bond-donor motif

V. Dichiarante, T. Kaiho, P. Metrangolo, T. Pilati, G. Resnati, G. Terraneo and M. Ursini, Chem. Commun., 2019, 55, 4234 DOI: 10.1039/C9CC01092K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements