The progress in the chemistry and bioactivity of 354 natural lindenane sesquiterpenoids (LSs) and their oligomers since 1925 is systematically summarized, focusing on the classification of their structures, chemical synthesis, and bioactivities.
This review summarizes the structural diversity, bioactivities, and biomimetic synthesis of [2 + 2]-type cyclobutane natural products, along with discussion of their biosynthesis, stereochemical analysis, racemic occurrence, and biomimetic synthesis.
DFT calculation revealed that that hydrogen bond interaction plays an important role in the endo-selectivity of the Diels-Alder reaction between lindenane sesquiterpenes promoted by pyridines.
A personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products, such as shimianolide A from Chloranthus holostegius var. shimianensis.
This review outlines recent progress in the total synthesis of cyclopropane-containing natural products, with a particular focus on the application of novel synthetic methodologies and tactics for assembling naturally occurring three-membered rings.