The core skeleton syntheses of 3′H-spiro[cyclohexane-1,1′-isobenzofuran]-2,5-dien-4-one 3 were explored. Then, two key skeleton molecules (5ah and 6d) were successfully constructed in 78% and 39% overall yields.
Herein, the synthesis of 4H-quinolizin-4-ones from N-(2-methoxy-2-oxoethyl) pyridinium salts and alkenes through dearomative cycloaddition and rearomative ring expansion has been developed.
A practical and efficient synthetic method has been developed for the construction of 3-selenylated chromones through the tandem cyclization of enaminones with diselenides in the presence of Selectfluor.
Exploring the utilization of earth-abundant metal oxide for sustainable essential organic transformation for industrial applications.
Tyrosinase inhibitors have potential applications in pharmaceutical and cosmetic products, and also in the food industry.