Multifunctional Nanoparticles in Traumatic Brain Injury: From Targeted Imaging and Diagnosis to Innovative Therapeutics

Nouran Alwisi, Sarah Aqel, Janatul Naeim, Dana Al-Hashimi, Samer El Hayek, Firas Kobeissy and Abdullah Shaito

IJN, 2026, Volume 21, 1
DOI: 10.2147/IJN.S557140

Pristimerin Alleviates Nanoparticulate Titanium Dioxide-Triggered Neurodegeneration in Hippocampal and Cortex by Downregulation of Inflammation and Oxidative Damage

Yungang Wang, Guodong Zhang, Lixiang Wang, Zhenguo Cheng and Zhenwu Zhao

Biol Trace Elem Res, 2026, 204, 3726
DOI: 10.1007/s12011-025-04928-z

Surface-functionalized nanoparticles for targeted drug delivery across the blood-brain barrier: advances and challenges in neurodegenerative disease therapy

G. Pramoda, Rahul K. Verma, Prashant Kesharwani and Rahul Shukla

Journal of Molecular Liquids, 2025, 433, 127938
DOI: 10.1016/j.molliq.2025.127938

SPAchips: Microparticles Used for the Selective In Vitro Labelling of Microglia

Justyna Gargas, Justyna Janowska, Beata Dabrowska-Bouta, Marta Sidoryk-Wegrzynowicz, Alberto M. Hernández-Pinto, Rubén Miguez, Teresa Suárez, Lidia Struzynska and Joanna Sypecka

IJMS, 2025, 26, 9773
DOI: 10.3390/ijms26199773

Nanoparticle-based strategies for overcoming the blood-brain barrier in CNS disorders and brain cancer: precision diagnostics and therapeutics for Alzheimer’s, Parkinson’s, multiple sclerosis, and glioblastoma

Hossein Feyzbakhsh

Tissue Barriers, 2025
DOI: 10.1080/21688370.2025.2599564

From Bench to Brain: Translating EV and Nanocarrier Research into Parkinson’s Disease Therapies

Barathan Muttiah and Nur Atiqah Haizum Abdullah

Biology, 2025, 14, 1349
DOI: 10.3390/biology14101349

Silicon quantum dots for neurotheranostic applications in dopamine detection

Shi Tang, Ling Lv, Na Liu, Xuewen Xu, Haishan Zhang and Shasha Yu

J Nanobiotechnol, 2026
DOI: 10.1186/s12951-026-04459-2

Neuromodulation with low-intensity pulsed ultrasound (Lipus) combined with curcumin-gold nanoparticles (Cur-AuNPs) in an Alzheimer's disease model

Laura de Roch Casagrande, Eduarda Behenck Medeiros, Ligia Milanez Venturini, Rubya Pereira Zaccaron, Camila da Costa, João Vitor Silvano Bittencourt, Henrique Borba Modolon, Adrielly Vargas Lidio, Sabrina Arcaro, Josiane Budni, Yaodong Gu, Anand Thirupathi and Paulo Cesar Lock Silveira

Drug Delivery, 2025, 32
DOI: 10.1080/10717544.2025.2577826

Smart micro/nanorobots for drug delivery in the brain

Di Shi, Xiang Wang, Yulin Deng, Huaijuan Zhou, Yilong Wang, Paul K. Chu and Jinhua Li

Progress in Materials Science, 2026, 155, 101533
DOI: 10.1016/j.pmatsci.2025.101533

Neurotoxicity and mechanism of metal and metal oxide nanoparticles

Shouying Cao, Meng Tang and Changcun Bai

Chemico-Biological Interactions, 2026, 428, 111953
DOI: 10.1016/j.cbi.2026.111953

Nanoparticles in Heavy Metal‐Induced Neurodegenerative Disorders: A Review

Vinod Kumar Nelson, Umme Hani, Nazima Haider, Farhat Fatima, Anoop Bodapati, Punna Rao Suryadevara, Priyadharshini Gogu, Selvankumar Thangaswamy and Gandhodi Gopi

Polymers for Advanced Techs, 2025, 36
DOI: 10.1002/pat.70383

Memory and mood-enhancing neuroprotective effects of visible light photoactivated gold nanoparticles and PEG3350 coating in a rat animal model

Paula Alexandra Postu, Radu Ionita, Daniela Angelica Pricop, Elena-Laura Ursu, Georgiana Bulai, Laurentiu Valentin Soroaga, Alina Nicolescu and Lucian Hritcu

Biomaterials Advances, 2026, 186, 214902
DOI: 10.1016/j.bioadv.2026.214902

Nanoparticle-Based Strategies to Enhance Catecholaminergic Drug Delivery for Neuropsychiatric Disorders: Advances, Challenges, and Therapeutic Opportunities

Luis E. Cobos-Puc, María del C. Rodríguez-Salazar, Sonia Y. Silva-Belmares and Hilda Aguayo-Morales

Future Pharmacology, 2025, 5, 51
DOI: 10.3390/futurepharmacol5030051

Nanoparticles: a new frontier in neurodegenerative disease therapy

Vipin Kumar, Shivani Sharma and Anchal Singh

Front. Med. Technol., 2025, 7
DOI: 10.3389/fmedt.2025.1654003

Nanobiotechnology-Based Strategies for Targeting Neuroinflammation and Neural Tissue Engineering

Tejas Yuvaraj Suryawanshi, Neha Redkar, Akanksha Sharma, Jyotsna Mishra, Sumit Saxena and Shobha Shukla

Immuno, 2026, 6, 18
DOI: 10.3390/immuno6010018

Histological and immunohistochemical alterations in the brain tissues induced by the subchronic toxicity of gold nanoparticles: In vivo study

Bashir Jarrar, Mansour Almansour, Amin Al-Doaiss, Qais Jarrar, Sun-Jun Lee and Amal Sewelam

Hum Exp Toxicol, 2025, 44
DOI: 10.1177/09603271251390978

Targeted Drug Delivery in Animal Models of Demyelination: The Role of Plant-Based Nanoparticles with a Focus on Multiple Sclerosis

Amirali Ebrahimbabaei, Mahmoud Osanloo, Ali Ghanbariasad and Manzarbanoo Shojaeifard

Mol Neurobiol, 2026, 63
DOI: 10.1007/s12035-025-05632-8

From Polyphenols to Prodrugs: Bridging the Blood–Brain Barrier with Nanomedicine and Neurotherapeutics

Masaru Tanaka, Adriano Cressoni Araujo, Vítor Engrácia Valenti, Elen Landgraf Guiguer, Vitor Cavallari Strozze Catharin, Cristiano Machado Gualhardi, Eliana de Souza Bastos Mazuqueli Pereira, Ricardo de Alvares Goulart, Rafael Santos de Argolo Haber, Atonelly Cassio Alves de Carvalho and Sandra Maria Barbalho

IJMS, 2026, 27, 2370
DOI: 10.3390/ijms27052370

Neuroprotective role of phenolic acids: mechanistic insights into cognitive decline and neurodegenerative disorder

Kunal Balwant Patil, Sinoy Sugunan, Anirudh Padiyar, Ashwini Kumar Mishra and Smita Jain

Nutritional Neuroscience, 2026, 1
DOI: 10.1080/1028415X.2026.2669234

SUBMICROSCOPIC CHANGES IN HIPPOCAMPAL NEUROCYTES OF RATS WITH INDUCED COLON ADENOCARCINOMA UNDER CONDITIONS OF NANOMATERIAL CORRECTION

I. O. CHEBERNINA and Z. M. NEBESNA

ШХ, 2026, 148
DOI: 10.11603/2414-4533.2026.1.16100

Metal coordination-based nanomaterials: Novel drug delivery system for treatment of rheumatoid arthritis

Paolo Coghi, Zihan Chen, Ka Fai Leong, Xi Yu, Narayan S. Hosmane and Yinghuai Zhu

Coordination Chemistry Reviews, 2026, 546, 217049
DOI: 10.1016/j.ccr.2025.217049

Recent Advances in Nanoparticle-Based Drug Delivery Strategies to Cross the Blood–Brain Barrier in Targeted Treatment of Alzheimer’s Disease

Hoa Le, Giang T. T. Vu, Amos Abioye and Adeboye Adejare

Pharmaceutics, 2026, 18, 192
DOI: 10.3390/pharmaceutics18020192

Rational Design and Optimisation of CRISPR‐Cas9 Delivery Systems for Targeted Genomic Transformation

Kalpana Pandya, Likshit S. Jaisinghani, Avanish Tripathi, Dileep Kumar, Sunny Kumar Saraf, Jagannath Sahoo and Devendra Kumar

The Journal of Gene Medicine, 2026, 28
DOI: 10.1002/jgm.70095