Ultrasound-responsive nanoweapons: covalent organic frameworks for cancer sonodynamic therapy

Yu Zhang, Chunyuan Hou, Bin Zhu, Nan Han, Jun Wan, Shujun Feng and Jun Luo

J. Mater. Chem. B, 2025, 13, 6896
DOI: 10.1039/D5TB00618J

The application of the pillararene-based GSH depletion strategy in tumor therapy

Yuqing Liu, Mengqi Liu, Shaoqi Xie, Juping Ma, Weiqi Han, Tong Sun and Bing Lu

Chem. Commun., 2026, 62, 11273
DOI: 10.1039/D6CC02664H

Near-infrared-activated Ru(ii)-nile blue conjugates as type-I photosensitizers for efficient hypoxia tumor therapy

Pengmin Shi, Zhiyuan Zhou, Yanyan Sun, Qinshen Xie, Chuanzhu Gao, Gang Xu, Jian Zhao and Lei Fang

Chem. Commun., 2025, 61, 18168
DOI: 10.1039/D5CC03927D

Gas-mediated reinforcement of cancer therapies: emerging strategies and future perspectives

Fang Yuan, Lu Wang, Lulu Ning, Jianjian Zhang and Yuan Guo

Chem. Sci., 2025, 16, 20108
DOI: 10.1039/D5SC04798F

Switching between type I/II photosensitization processes for of an unconventional dye as modulated by the tumor microenvironment for inducing immunogenic death

Lei Hao, Yumei Wang, Shuang Zeng, Zhuo Yang, Saran Long, Wen Sun, Jingyun Wang, Xiaojun Peng and Haidong Li

Chem. Commun., 2025, 61, 10981
DOI: 10.1039/D5CC02308D

Glycofullerene–corrole hybrids: a new class of multifunctional nanomaterials with potential in targeted photodynamic therapy

Jennifer Patino-Alonso, Carla I. M. Santos, Adriana F. Cruz, Sandra Pinto, Justo Cabrera-González, M. Amparo F. Faustino, M. Graça P. M. S. Neves, Ermelinda M. S. Maçôas, Nazario Martín and Beatriz M. Illescas

Chem. Sci., 2026, 17, 3339
DOI: 10.1039/D5SC06977G

Construction of smart switchable nanoplatforms for adaptive phototheranostics

Yuewen Yu, Yubo Liu, Le Zhang, Congbin Fan, Ben Zhong Tang and Guangxue Feng

Chem. Soc. Rev., 2026, 55, 2325
DOI: 10.1039/D5CS00736D

Enhancing photodynamic therapy effects by a glutathione-responsive SO2 donor as a nanocarrier for cancer therapy

Shaoqi Xie, Mengqi Liu, Yuqing Liu, Jiachen Xia, Tong Sun and Bing Lu

Chem. Commun., 2026, 62, 6368
DOI: 10.1039/D6CC00058D

Carboxyl-functionalized flavin as efficient heavy-atom-free triplet photosensitizers: a theoretical investigation

Huimin Guo, Heping Li and Chengyu Yang

Phys. Chem. Chem. Phys., 2026, 28, 12551
DOI: 10.1039/D6CP00754F

Bioengineered nanomaterials for dynamic diagnostics in vivo

Jizhong Wu, Xinyu Zhou, Chung Yin Tsang, Qingsong Mei and Yong Zhang

Chem. Soc. Rev., 2025, 54, 5470
DOI: 10.1039/D5CS00136F

Acidic pH-triggered covalent cross-linking of AIE nanoparticles for enhanced tumor imaging and photodynamic therapy

Weiqi Zai, Huiling Ji, Jincheng Li, Jing Wang, Hongli Chen, Dan Ding, Shenglu Ji and Nannan Wang

Biomater. Sci., 2026, 14, 1703
DOI: 10.1039/D5BM01655J

NIR-activatable aza-BODIPY nanoparticles for photoacoustic imaging and synergistic NO–photothermal cancer therapy

Qian He, Jiawen He, Panyue Wen, Haochen Guo, Masaru Tanaka, Shizhong Luo, Junjie Li, Ye Liu, Liewei Wen and Chenzhi Yao

Biomater. Sci., 2025, 13, 5369
DOI: 10.1039/D5BM00937E

Microbial therapeutics for cancer: emerging strategies and biomedical applications

Meng Chen, Yupei Hu, Xiaozhen Zhou, Lili Xia, Chenyao Wu, Yu Chen and Wei Feng

Chem. Commun., 2025, 61, 14531
DOI: 10.1039/D5CC03618F

Organic photosensitizers: from molecular design to phototheranostics

Tian Zhang, Xinyu Qu, Jinjun Shao and Xiaochen Dong

Chem. Soc. Rev., 2025, 54, 8406
DOI: 10.1039/D5CS00599J

Thermosensitive liposomal nanomedicine-functionalized photothermal composite scaffolds for light-guided cancer therapy

Xiaohan Liu, Huajian Chen, Man Wang, Tianjiao Zeng, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang and Guoping Chen

Mater. Horiz., 2025, 12, 8654
DOI: 10.1039/D5MH00888C

Ru(ii) complexes in antibacterial phototherapy: emerging strategies for combating bacterial infections

Qipeng Yuan, Jiayan Huang, Kangqi Guan, Xia Zhou, Ying Xiong, Siping Wei, Lin Yang and Yao Jian

Chem. Commun., 2026, 62, 8340
DOI: 10.1039/D6CC01012A

Frontiers in photodynamic therapy: type I NIR-II photosensitizers with aggregation-induced emission features

Ye Tong, Xue Li, Dong Wang and Ben Zhong Tang

Chem. Commun., 2026, 62, 83
DOI: 10.1039/D5CC05375G

NIR-activated dual-mode oxygen-generating and -delivering nanoplatform for enhanced photodynamic therapy of cervical cancer

Jiaxing Li, Chenyang Chu, Lijun Zhu, Zhong Du, Yaqi Cui, Jiabao Xiong, Chi Zhang, Yuxiang Gao, Biao Dong and Nuernisha Alifu

J. Mater. Chem. B, 2026, 14, 3427
DOI: 10.1039/D5TB02652K

Multifunctional nanomaterials for dental photo-theranostics

Yujia Shi, Xiaolin Sun, Jiao Fang, Chunyan Li, Biao Dong, Manlin Qi and Lin Wang

Chem. Soc. Rev., 2026, 55, 30
DOI: 10.1039/D5CS00825E

Bismuth selenide nanoflowers for internal irradiation combined with photothermal therapy for tumor sensitization and killing

Jiage Gong, Qi Wang, Ruoqi Wang, Jianhua Chen, Jie Gao, Jiangfeng Du and Jianguo Li

Nanoscale Adv., 2025, 7, 7519
DOI: 10.1039/D5NA00270B

Dual-target regulation of glutathione and heat shock proteins via molecular-carrier-pathway triple-engineering for potentiated phototherapy

Yike Tu, Laiping Fang, Shufang Li, Kuo He, Yanzhao Diao, Lifeng Hang, Lina Wang, Jianan Dai, Ping’an Ma and Guihua Jiang

Mater. Horiz., 2025, 12, 6291
DOI: 10.1039/D5MH00614G

Molecularly engineered BODIPY photosensitizers for combined cancer phototherapy and immunotherapy

Huixia Wang, Yangming Zhang and Mengjiao Zhou

Front. Pharmacol., 2026, 17
DOI: 10.3389/fphar.2026.1849977

Progress and challenges in photodynamic therapy for cervical lesions in China

Lihua Qiu and Wen Di

gocm, 2025, 5, e000246
DOI: 10.1136/gocm-2025-000246

Injectable hydrogels for cancer phototherapy

Yin Xu, Yuxin Guo, Xiaochen Wu, Wenjun Wang, Peng Chen, Lu-Lu Qu and Xiaochen Dong

Progress in Materials Science, 2026, 160, 101683
DOI: 10.1016/j.pmatsci.2026.101683

Machine Learning‐Assisted Design and Discovery of High‐Performance Cyanine‐Based Photosensitizers for Integrated Theranostic Applications

Bowen Diao, Shaoyang Shi, Junhan Li, Letao Yang, LingFeng Zheng, Hongxiang Guo and Xiaojun Peng

Advanced Materials, 2026, 38
DOI: 10.1002/adma.202515813

Ir(III) complexes for photo-activated mitochondrial G-quadruplex damage against cisplatin-resistant cancer cells

Shuqi Huang, Jinrong Yang, Kai Xiong, Yu Chen and Hui Chao

Journal of Inorganic Biochemistry, 2026, 282, 113364
DOI: 10.1016/j.jinorgbio.2026.113364

Modulating de-excitation pathways of BF2 Formazanate dyes via donor substituent engineering for NIR-II phototheranostics

Hanming Dai, Jinjun Shao, Dan Lei, Weili Wang, Leichen Wang, Peng Chen, Feng Jiang and Xiaochen Dong

Chemical Engineering Journal, 2026, 529, 173119
DOI: 10.1016/j.cej.2026.173119

Endoplasmic Reticulum-Targeted Phototherapy Remodels the Tumor Immunopeptidome to Enhance Immunogenic Cell Death and Adaptive Anti-Tumor Immunity

Weidong Xiao, Mingquan Gao, Banghui Mo, Xie Huang, Zaizhi Du, Shufeng Wang, Jianhong Chen, Shenglin Luo and Haiyan Xing

Pharmaceuticals, 2025, 18, 491
DOI: 10.3390/ph18040491

Harnessing Lignin-Derived Carbon Dots for Enhanced NIR Photothermal Ablation of Melanoma Cells

Vinita Satwani, Badri Narayana Sahoo, Kallayi Nabeela, Abhijeet Joshi and Shaikh M. Mobin

ACS Omega, 2025, 10, 39555
DOI: 10.1021/acsomega.5c02344

Tumor-microenvironment activatable organic photosensitizers for cancer photodynamic therapy

Shu Qin, Yurong Liu, Jinjun Shao, Zewei Luo, Peng Chen, Peng Huang and Xiaochen Dong

PXLIFE, 2026, 1, 9
DOI: 10.3724/PXLIFE.2025-0011

Azobenzene-cyanine hybrids with enhanced photostability and non-radiative transitions for multimodal tumor therapy

Xiang Sun, Dongdong Chen, Yuqin Chen, Huanren Cheng, Ruping Huang, Juan Jin, Wanghanqi Yang, Bin Huang and Ning Gu

Bioactive Materials, 2026, 61, 339
DOI: 10.1016/j.bioactmat.2026.01.048

Illuminating oral health: AIEgens for phototheranostics

Jingyuan Chen, Wenhao Yan, Xinyu Wang, Chen Gao, Ziyu Hong, Zhiqiang Li, Lin Wang, Qihang Ding, Shi Chen, Zhen Cheng and Meijia Gu

Cell Biomaterials, 2025, 1, 100012
DOI: 10.1016/j.celbio.2025.100012

Terminal branch twisting induced molecular distortion: A strategy for advanced NIR-II photothermal/photodynamic therapy

Xiaoye Chen, Yu Cheng, Ding Tan, Yan Sun, Yu Gao and Haijun Chen

Journal of Photochemistry and Photobiology A: Chemistry, 2026, 474, 116999
DOI: 10.1016/j.jphotochem.2025.116999

Oxygen Self-Sufficient Ir–MnII/III Coordination-Assembled Nanoparticles Evoke Apoptosis and Ferroptosis for Boosting Hypoxic Melanoma Photoimmunotherapy

Zixin Tang, Jun Shu, Ai-Ling Luo, Xianbo Wu, Tao Feng and Hui Chao

ACS Nano, 2026, 20, 5271
DOI: 10.1021/acsnano.5c21399

Multifunctional Gold Super‐Nanoparticle‐Based Nanosystem for SERS‐Guided Oxygen‐Independent Phototherapy

Jiamin Guo, Na Feng, Yuanzhu Liu, Liyan Liu, Yawen Zhang, Xinjian Yang and Enjun Wang

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202500537

Fluorinated charge-reversible phthalocyanine nanoemulsions for glioma-targeted dual-modal imaging and self-oxygenated phototherapy

Tingjuan Wu, Qiao Yu, Jing Zhang, Lijun Zhu, Chaohui Ye, Xin Zhou, Yu Li and Zhong-Xing Jiang

Materials Today Bio, 2026, 38, 103269
DOI: 10.1016/j.mtbio.2026.103269

Regioisomerization of bromine atom on end group to enhance photodynamic activity of A−D−A photosensitizer

Shaoqi Xie, Mengqi Liu, Yuqing Liu, Jiachen Xia and Bing Lu

Journal of Photochemistry and Photobiology A: Chemistry, 2026, 474, 117003
DOI: 10.1016/j.jphotochem.2025.117003

A Molecular Trimming Strategy for Hypoxia‐Tolerant Photosensitizers With Enhanced cGAS‐STING Activation

Dan Li, Yao Tu, Feng Chen, Jiayao Jiang, Tao Jin, Yongjie Zhu, Guoqing Wen, Sha Feng, Xintong Lin, Deliang Wang, Oliver S. Wenger, Huaiyi Huang, Bizhu Chu and Pingyu Zhang

Angewandte Chemie, 2026
DOI: 10.1002/ange.1516189

Aza-BODIPY dye with D-π-A architecture for 1064 nm laser-triggered photothermal theranostics

Di An, Weinan Jiang, Ziyang Zhang, Shupan Wang, Weili Wang, Chunyang Miao, Jinjun Shao and Xiaochen Dong

Sensors and Actuators B: Chemical, 2025, 442, 138144
DOI: 10.1016/j.snb.2025.138144

Editorial: Innovative strategies and advancements in phototherapy for enhanced cancer treatment

Leonardo Bianchi, Leopoldo Sitia, Gabriela Paroni and Sanjeev Soni

Front. Med., 2026, 13
DOI: 10.3389/fmed.2026.1789533

Recent Advances in Nano-Drug Delivery Strategies for Chalcogen–Based Therapeutic Agents in Cancer Phototherapy

Subhrakant Jena and Abderrazzak Douhal

IJMS, 2025, 26, 4819
DOI: 10.3390/ijms26104819

Engineered plant extracellular vesicles: Emerging nanoplatforms for combinational cancer immunotherapy

Fucai Chen, Rongrong Bao, Wanyi Yang, Yijing Lu, Jiaxin Guo, Wenjing Chen, Jiale Li, Kuanhan Feng, Wen Zhang, Liuqing Di, Liang Feng and Ruoning Wang

Acta Pharmaceutica Sinica B, 2025, 15, 5663
DOI: 10.1016/j.apsb.2025.08.020

Regioisomeric Engineering of Sterically Hindered Bright Near-Infrared Paraptosis Agents for Chemo-Photodynamic Therapy

Xiang Wang, Xiaowan Han, Xiaoyuan Tian, Hosoowi Lee, Caihong Xiang, Chaorui Wang, Liang Luo, Hai-Yu Hu, Guangle Niu and Juyoung Yoon

J. Am. Chem. Soc., 2025, 147, 27068
DOI: 10.1021/jacs.5c10005

Biodegradable and biocompatible poly(lactic acid) optical fibers for fiber-guided photothermal therapy of breast cancer cells in vitro

Shengli Pan, Shuyuan Zhu, Li Chen, Yiqian Fu, Jingyuan Yao, Bo Liu, Tao Ye, Chris Zhou, Orlando J. Rojas, Xin Lu, Xiuhong Wang and Pu Wang

Biomed. Opt. Express, 2026, 17, 2024
DOI: 10.1364/BOE.589657

Photothermal agents in cancer therapy: Applications and development prospects

Shiyu He, Shuaipeng Feng, Yiming Han, Qingqing Xu, Jiaru Lan, Donghua Di, Da Wang, Siling Wang, Huan Zhai and Qinfu Zhao

Chemical Engineering Journal, 2026, 178517
DOI: 10.1016/j.cej.2026.178517

Facile Preparation of Nanoscale Chlorin-Integrated Covalent Organic Frameworks for Combined Chemophototherapy

Xiaohua Zheng, Min Chen, Xinran Wang, Junjie Wu, Xiaohui Wang, Jiayi Chen, Shanmei Wang, Mengjiao Zhou, Weiqi Wang and Rui Xia

Biomacromolecules, 2026, 27, 580
DOI: 10.1021/acs.biomac.5c01831

A Molecular Trimming Strategy for Hypoxia‐Tolerant Photosensitizers With Enhanced cGAS‐STING Activation

Dan Li, Yao Tu, Feng Chen, Jiayao Jiang, Tao Jin, Yongjie Zhu, Guoqing Wen, Sha Feng, Xintong Lin, Deliang Wang, Oliver S. Wenger, Huaiyi Huang, Bizhu Chu and Pingyu Zhang

Angew Chem Int Ed, 2026
DOI: 10.1002/anie.1516189

Liposomal Nanoconfinement Enables Type I Photodynamic Conversion for Synergistic Cancer Photothermal‐Immunotherapy

Minglu Zhang, Shanshan Liang, Meng Wang, Tingfeng Zhang, Jinke Liu, Yuyuan Peng, Hao Fang, Lingna Zheng, Xiao He, Meng Wang, Luling Wu, Tony D. James, Wei Zhao, Bing Wang and Weiyue Feng

Advanced Science, 2026, 13
DOI: 10.1002/advs.202515013

Pyrrolopyrrole Cyanine-Based Polymer with Superior Multifunctionality for Boosting Cancer Phototheranostics

Xue Meng, Yingnan Xu, Yuan Zhang, Huaxin Zhu, Jianwen Song, Ji Qi, Wenqiang Qiao and Di Zhang

ACS Materials Lett., 2025, 7, 1431
DOI: 10.1021/acsmaterialslett.5c00259

A hypoxia-activated photothermal agent suppressing thermotolerance and secondary inflammation for enhanced tumor ablation

Kaiye Wang, Yuting Jia, Xiaohan Liu, Wei Pan, Xiuyan Wan, Na Li and Bo Tang

Chinese Chemical Letters, 2026, 37, 111589
DOI: 10.1016/j.cclet.2025.111589

Harnessing Targeted Photodynamic Therapy to Synergistically Activate T Cell and NK Cell Responses in Multiple Myeloma

Zhaoyun Liu, Xiaohan Liu, Jingyi Ma, Yuan Zhang, Mengjie Ye, Hui Liu, Kai Ding, Jia Song, Rong Fu and Ji Qi

Advanced Materials, 2026, 38
DOI: 10.1002/adma.202518663

Glycyrrhizic acid-based nanotheranostic system to enhance photothermal immunotherapy by suppressing HSP90 and remodeling tumor microenvironment

Yihan Wu, Chenglin He, Yu Huang, Zhen Liu, Ying Zhu, Manyin Zhang, Jingjing Li, Yu You, Yitao Wang, Tao Chen and Jinming Zhang

Materials Today Bio, 2025, 35, 102353
DOI: 10.1016/j.mtbio.2025.102353

Illuminating gene delivery: Insights into the light-induced gene delivery systems with emphasis on mRNA therapeutics

Yongyi Xie, You Zhou, Jiaxin Guo, Zhongqian Zhang, Yongcheng Zhu, Ewa M. Goldys, Wei Deng and Wenjie Chen

Materials Today, 2025, 88, 959
DOI: 10.1016/j.mattod.2025.06.034

Microglial Membrane‐Coated Biomimetic Nanoplatform for Enhanced Blood–Brain Barrier Penetration and Targeted Photodynamic Therapy in Orthotopic Glioblastoma

Jie Li, Xiaoyu Xu, Yuhang Zhao, Xuan Wu, Siyu Chen, Jiange Xu, Rong Xiao, Jing Tang, Xuechuan Hong, Shi Chen, Zhiqiang Li and Meijia Gu

Adv Healthcare Materials, 2026, 15
DOI: 10.1002/adhm.202502808

Engineering the tumor immune landscape: Translating non‐invasive physical stimulation into tumor‐associated macrophage‐targeted cancer immunotherapy

Tingyu Zhang, Jie Lan, Wangrui Peng, Huai Yang, Yiyang Huang, Linyuan Jin, Meng Du and Zhiyi Chen

Bioengineering & Transla Med, 2026
DOI: 10.1002/btm2.70126

Implantable Biophotonic Device for Wirelessly Cancer Real‐Time Monitoring and Modulable Treatment

Renhao Nie, Qingyan Jia, Yuanying Li, Changhan Yan, Xiyin Liu, Yaolan Tao, Jianhong Zhang, Peng Li and Wei Huang

Advanced Science, 2025, 12
DOI: 10.1002/advs.202503778

Well-tailored Photosensitizers with Boosted Type-I ROS Generation by Fluorination Strategy for Precise Near-infrared Fluorescence-guided Photodynamic Therapy

Yuxuan Gao, Qiyu Kong, Jun Wang, Fengwei Sun, Xinyu Liu, Deliang Wang, Jiangao Li and Zhen Yang

Chem. Res. Chin. Univ., 2026, 42, 534
DOI: 10.1007/s40242-026-5314-y

An AIE-active Janus filter membrane for highly efficient detection and elimination of bioaerosols

Saisai Yan, Qing Liu, Zishu Wen, Bing Liang, Zhanjie Liu, Jiyao Xing, Jiyixuan Li, Miao Zhang, Xinlin Liu, Chao Wang and Dongming Xing

Journal of Hazardous Materials, 2025, 492, 138116
DOI: 10.1016/j.jhazmat.2025.138116

Molecular Scaffolding Engineering Generates High‐Efficiency Anti‐Quenching Small Molecules for NIR‐IIb Fluorescence Imaging and Phototheranostic Applications

Pengfei Chen, Qingxin Zeng, Bokai Liu, Kai Chen, Zikun Yu, Yansu Lan, Changjiang Li, Pengfei Sun, Zhiyao Li, Chongzhi Wu, Bowen Li and Quli Fan

Adv Funct Materials, 2026, 36
DOI: 10.1002/adfm.202529470

Photoinduced Proton-Transfer-Mediated Molecular Recognition in Molecular Crystals

Lishan Sun, Tianyan Zhang, Yanxue Che, Jiangfan Shi, Yangyang Ren, Yan Yan, Hongwei Ji, Wenjing Song, Yanjun Gong, Ling Zang, Yanke Che and Jincai Zhao

Anal. Chem., 2025, 97, 10010
DOI: 10.1021/acs.analchem.5c00876

Recent Advances in Nanomedicine for Targeted Phototherapy in Head and Neck Cancer

Hongshuai Liu, Chen Lin, Wenying Li, Linrong Wu, Zihao Xia, Yi Wu, Yanqi Huang, Shanshan Gu, Junjun Zhang and Zhisen Shen

IJN, 2026, Volume 21, 1
DOI: 10.2147/IJN.S596902

Ferroptosis-driven anti-heat endurance augments photothermal-therapy of uveal melanoma via a multifunctional liposome

Shuyue Zhang, Yuming Chen, Houli Zhong, Haiyan Mi, Wanjun Dong, Da Zhang and Zhongjiang Chen

Colloids and Surfaces B: Biointerfaces, 2026, 266, 115811
DOI: 10.1016/j.colsurfb.2026.115811

Progress in the integration of 3D printing technology with photothermal materials for osteosarcoma treatment

Yue Zheng, Hanqi Lou, Zhen Gao, Ling Zhu, Yiwei Zhang, Haiyang Lin, Zilin Li, Xiaokun Yue, Weize Kong, Hao Yang, Zhouhao Chen, Zhiang Hu, Xin Liu, Xinming Su, Jinwu Wang and Junjie Niu

Adv Compos Hybrid Mater, 2025, 8
DOI: 10.1007/s42114-025-01405-y

Metal-based nanomaterials for cancer phototherapy: current advancements and translational challenges

Hao Su, Xinyu Zhao, Wenchao Xu, Huanlan Sa, Xiaohan Li, Zhibing Liu, Fangling Ning, Mianli Li and Zhijing He

Front. Pharmacol., 2026, 17
DOI: 10.3389/fphar.2026.1841081

Twisted D-π-A-π-D boron difluoride formazanate dye enabling SOCT-ISC for NIR-II fluorescence and Type I photodynamic therapy

Ziyang Zhang, Leichen Wang, Anqing Mei, Weili Wang, Kang Xu, Jinjun Shao, Su Jing and Xiaochen Dong

Sensors and Actuators B: Chemical, 2026, 466, 140369
DOI: 10.1016/j.snb.2026.140369

Charge Transfer-Mediated J-Aggregates of Azaindole Cyanine with 160 nm Absorption Redshift for Efficient NIR-II Photothermal Tumor Therapy

Tiancong Shi, Xi Chen, Xiaolong Li, Xin Li, Yang Zhao, Hongyi Zhang, Fuping Han, Lihan Cai, Xiao Zhou, Yan Su, Wen Sun, Jianjun Du, Jiangli Fan and Xiaojun Peng

ACS Nano, 2025, 19, 27845
DOI: 10.1021/acsnano.5c09082

Metal–polyphenol network-based multifunctional materials for tumor therapy: Intrinsic properties, advances, and applications

Chen Ma, Qian Xu, Lingwen Ding, Xinya Liu, Junkai Cheng, Yiman Wang, Lu Liu, Jiaqi Xian, Jian Gu, Phuong-Thao Tran, Qin Wang, Shuai Wang and Fen-Er Chen

Acta Pharmaceutica Sinica B, 2026, 16, 1421
DOI: 10.1016/j.apsb.2025.11.038

Artificial intelligence driven workflow for accelerating design of novel photosensitizers

Hongyi Wang, Xiuli Zheng, Weimin Liu, Zitian Tang and Sheng Gong

AI Sci., 2026, 2, 015002
DOI: 10.1088/3050-287X/ae4412

Compatible Fluorescent-Afterglow Luminescent Probe Enables Quantification of Photochemical Reaction-Driven Tumor Theranostics

Lili Teng, Jia Xie, Qiao Tang, Yanan Zhang, Chang Zuo, Beining Chang and Yongchao Liu

Anal. Chem., 2026, 98, 11212
DOI: 10.1021/acs.analchem.5c07719

Rational design of AIEgens through π-bridge engineering for dual-modal photodynamic and photothermal therapy

Yanwen Liu, Shunzhi Gou, Hongchao Wang, Yumei Wu, Mingyan Yang, Xinmin Li, Hongyu Li, Zhe Zheng, Zeli Yuan and Jie Gao

Bioorganic & Medicinal Chemistry, 2025, 119, 118081
DOI: 10.1016/j.bmc.2025.118081

Strategies to enhance the effects of nanotechnology-mediated photodynamic therapy

Yanhan Mo, Xu Liu, Jian You and Lihua Luo

Nanomedicine, 2025, 20, 2433
DOI: 10.1080/17435889.2025.2550233

Cyclic molecular rigidity dependent modulation of photodynamic and photothermal activities

Zhen Yang, Aoqing Jia, Zhigang Xie and Min Zheng

Chemical Engineering Journal, 2025, 526, 170868
DOI: 10.1016/j.cej.2025.170868

Advances in near-infrared responsive functional nanocomposites for bioimaging and antitumor research

Juan Wang, Xing Gao, Lei Feng, Deliang Zhang, Shuhua Lv, Xiaoyin Li, Qingjia Liu, Dongkun Yu, Miaomiao Xing, Dongrun Li, Lulu Suo, Hongyu Mou and Jibin Song

Journal of Controlled Release, 2025, 384, 113904
DOI: 10.1016/j.jconrel.2025.113904

Biohybrid system EcN@PB for reshaping tumor immunosuppressive microenvironment to improve photothermal therapy induced antitumor immune response

Qiang Feng, Hui Zhang, Guixian Ye, Jialiang Zhang, Jianbin Xiao, Zhiyu Wang, Jinyu Zhang, Meiqi Pan, Jukai Feng, Yang Zhong, Zhongying Shi, Jianmin Wang and Jingfeng Liu

Materials Today Bio, 2025, 35, 102495
DOI: 10.1016/j.mtbio.2025.102495

Synergistic S···O and S···H Conformational Locks for Planarity‐Enhanced NIR‐II Phototheranostics

Jiuhui Zhang, Jinjun Shao, Leichen Wang, Weili Wang, Jianqiu Chen and Xiaochen Dong

Adv Funct Materials, 2026, 36
DOI: 10.1002/adfm.202527041

Click, assemble, destroy: Bioorthogonal surface programming of nanophotosensitizers for precision cancer therapy

Ying Tang, Hao Kong, Xiaoying Hao, Min Gao, Wenbi Feng, Xueluer Mu, Yingxi Lu and Xianfeng Zhou

Journal of Colloid and Interface Science, 2025, 700, 138521
DOI: 10.1016/j.jcis.2025.138521

In-Cell NAD(P)H Photocatalysis with a Metal Complex for Photocatalytic Anticancer Therapy

Li Wei, Anyi Dao, Guotao Yuan, Pingyu Zhang and Huaiyi Huang

Acc. Chem. Res., 2025, 58, 2640
DOI: 10.1021/acs.accounts.5c00455

Multimodal Key Anti-Oncolytic Therapeutics Are Effective In Cancer Treatment?

Luyi Ye, Meng Gao, Yue Chen, Yuting Zhu, Jilong Wang and Zhangquan Wang

IJN, 2025, Volume 20, 9999
DOI: 10.2147/IJN.S531849

Coordination-Induced Supramolecular Assembly Enhances Singlet Oxygen Generation in Pt-BODIPY Photosensitizers for Synergistic Chemo-Photodynamic Therapy

Zhiwei Xu, Yunxia Song, Pengmin Shi, Yanyan Sun, Jingyin Xu, Lei Fang and Jian Zhao

Inorg. Chem., 2025, 64, 23476
DOI: 10.1021/acs.inorgchem.5c03659

Phototheranostics: An advanced approach for precise diagnosis and treatment of gynecological inflammation and tumors

Qihang Ding, Aoxue Guo, Shuai Zhang, Chuanqi Gu, Xinyu Wang, Xin Li, Meijia Gu and Jong Seung Kim

Biomaterials, 2025, 316, 123012
DOI: 10.1016/j.biomaterials.2024.123012

Photodynamic Therapy in Cancer: Insights into Cellular and Molecular Pathways

Vincenzo Papa, Fabiana Furci, Paola Lucia Minciullo, Marco Casciaro, Alessandro Allegra and Sebastiano Gangemi

CIMB, 2025, 47, 69
DOI: 10.3390/cimb47020069

Mitochondria-localized photocatalyst of biomimetic organic semiconductor nanoparticles for NIR-activatable photocatalytic immunotherapy

Yu Wang, Yijian Gao, Yuliang Yang, Jie Zhang, Yingpeng Wan, Xiliang Li, Ning Li, Guangtao Fu, Yuhui Yang, Zeng Li, Qi Zhao, Yuanfeng Chen and Shengliang Li

Sci. Adv., 2025, 11
DOI: 10.1126/sciadv.adx4850

Traditional Chinese Medicine Polysaccharides-Based Nano-Drug Delivery Systems: Design Strategies and Combination Platforms in Tumor Therapy

Qianru Chen, Yixuan Gan, Ruiyi Tang, Jianan Zhang and Di Wu

Life, 2026, 16, 838
DOI: 10.3390/life16050838

Enhancing mitochondria-targeted photodynamic therapy via synergistic mitophagy-ferroptosis by a peroxynitrite-activated near-infrared photosensitizer in triple-negative breast cancer

Jia Huang, Yuanyuan Wang, Wanting Zhang, Wei Zeng, Jiaoli Zhang, Dan Cheng, Longwei He and Jia Zhou

Sensors and Actuators B: Chemical, 2026, 446, 138728
DOI: 10.1016/j.snb.2025.138728

A multifunctional nanosystem based on sodium nitroprusside/copper co-doped dopamine-coated Prussian blue nanoparticles with enhanced photothermal capability for combined cancer therapy

Tao Liao, Jiahao Chen, Linwei Li, Jinyu Wang, Siyu Zhang, Jia Liu, Ying Kuang and Cao Li

Colloids and Surfaces B: Biointerfaces, 2026, 259, 115298
DOI: 10.1016/j.colsurfb.2025.115298

Recent Progress in Nanoparticle-Based Phototherapy Systems: New Insights Into Breast Cancer

Samaneh Rezaei, Najmeh Ahangari, Hamed Mirzaei and Maryam Mahjoubin-Tehran

BioNanoSci., 2026, 16
DOI: 10.1007/s12668-026-02634-1

Halogen-modified photosensitizers: Inducing mitochondrial dysfunction for tumor suppression

Duo-Duo Wei, Jianying He, Jie Zeng, Xin-Hao Han, Juan-Li Yuan, Bing Fan, Youlai Zhang, Xin-Hui Qu, Shaorong Huang and Xiao-Jian Han

Colloids and Surfaces B: Biointerfaces, 2026, 265, 115724
DOI: 10.1016/j.colsurfb.2026.115724

In situ therapeutic tumor-associated macrophage vaccines: Biomimetic hybrid metalloenzymes for effective combined tumor immunotherapy

Shunxin Tang, Wanying Sun, Xiaolu Guo, Fangmian Wei and Xing-Can Shen

Chemical Engineering Journal, 2025, 519, 165532
DOI: 10.1016/j.cej.2025.165532

PROTAC-powered synergistic tumor therapy

Xiaoyu Wang, Jingwen Zou, Yixuan Tao, Zhiwen Zhou, Changyu Bian, Zhiqiang Mao and Zhihong Liu

TrAC Trends in Analytical Chemistry, 2026, 196, 118678
DOI: 10.1016/j.trac.2026.118678

A Mitochondria‐Specific Nanomedicine for Synergistic Chemo‐Photothermal Therapy and Immunogenic Activation Against Breast Cancer

Min Li, Jiangqi Feng, Junyang Zhuang, Qingguo Zhong, Yanda Li, Yanzhuo Lv, Shaoteng Huang, Xiangyu Huang, Mingbo Zhang, Xiaofeng Cai, Yuxin Wang, Wenping Chen, Zhenyu Duan, Zhou Chen, Kui Luo and Ning Li

Advanced Science, 2026, 13
DOI: 10.1002/advs.202522226

NIR‐II Organic Phototheranostics: Matching Rotatable Donors and Shielding Acceptors for Enhanced Imaging and Phototherapy by Stabilized Triplet Excitons and Optimized Radiative Decay

Jianye Gong, Yue Zhang, Jianguo Wang and Guoyu Jiang

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202502527

Recent Advances in Tetrahedral Framework Nucleic Acids for Multimodal Synergistic Cancer Therapy

Zishan Huang, Zhitong Chen, Zhiyu Zhang, Hong Sun, Xujuan Li, Zhaogang Sun, Hongqian Chu and Wenjing Liu

Aggregate, 2026, 7
DOI: 10.1002/agt2.70330

A large π-conjugated organic photothermal agent for photoacoustic-guided photothermal therapy

Lihan Chen, Huihui Liang, Pei Wang, Huiyu Si, Youhui Zhang, Xin Lai, Honglong Zou, Kexin Zhou, Guodong Xu, Yonggui Song, Xin Zhou and Xunfan Liao

Dyes and Pigments, 2026, 245, 113166
DOI: 10.1016/j.dyepig.2025.113166

In-situ injectable hydrogel for near-infrared-regulated hyperthermic perfusion therapy of triple-negative breast cancer

Libin Zhai, Linwei Li, Tao Liao, Yi Zhu, Cao Li, Ziqiang Xu, Diwei Zheng and Wenqian Yu

Journal of Colloid and Interface Science, 2025, 690, 137228
DOI: 10.1016/j.jcis.2025.03.017

A Narrative Review on Photobiomodulation-Guided Immunomodulation: Reprogramming Tumor-Associated Macrophages

Dilpreet Singh

Photobiomodulation, Photomedicine, and Laser Surgery, 2026, 44, 1
DOI: 10.1177/25785478251406479

The synthesis, photophysical and biological properties of 5,10,15,20-tetra(4-substituted phenyl)tetrabenzoporphyrin derivatives

Ying Jiang, Hong-Yu Liang, Yi-Jia Yan, Igor D. Romanishkin, Gennady A. Meerovich, Igor V. Reshetov, Xing-Ping Zhou and Zhi-Long Chen

European Journal of Medicinal Chemistry, 2025, 291, 117612
DOI: 10.1016/j.ejmech.2025.117612

Highly emissive and stable polyphosphazene nanospheres by tetraphenylethylene for super-resolution imaging and cancer therapy

Qifei Shen, Peijuan Zhang, Tianyu Zhao, Daquan Wang, Pei Zhou, Ming Lei, Lingjie Meng and Dongfeng Dang

Sci. China Chem., 2025, 68, 6762
DOI: 10.1007/s11426-025-2955-9

Size-tuned PEGylated NIR-II fluorescent probes for high-contrast plant imaging and TMV detection

Fang Zhao, Yu-Ling Xu, Meng-Jiao Lu, Le Tu, Chong-Lu Li, You Dou, Jun Li, Xiang-Yang Li and Yao Sun

J Nanobiotechnol, 2025, 23
DOI: 10.1186/s12951-025-03452-5

AIE Gemini Surfactant-Enabled Janus Membrane for All-In-One “Sampling–Detection–Elimination” of Airborne Pathogens

Saisai Yan, Zishu Wen, Xuanzhe Wang, Yufeng Guan, Ning Du, Yingjie Zhong, Xinlin Liu, Ningning He, Shangyong Li, Dongming Xing and Peng Sun

Environ. Sci. Technol., 2026, 60, 7744
DOI: 10.1021/acs.est.5c17120

Strategically Designed Mitochondria‐Targeting AIEgens for Effective Eradication of Primary and Metastatic Tumors via Synergistic Phototherapy and Induced Immunogenic Cell Death

Lin Yang, Jiachang Huang, Yanan Liao, Deping Hu, Yake He, Na Feng, Ryan T. K. Kwok, Jacky W. Y. Lam, Jing Zhang, Benzhao He and Ben Zhong Tang

Adv Healthcare Materials, 2025, 14
DOI: 10.1002/adhm.202500513

Biomimetic cell membrane-mediated nanodelivery platform based on natural products: Emerging strategies for cancer combination therapy

Yingjie Jiang, Zonglan Hu, Yuyu Wei, Yufei Su, Yanrui Yang, Aikepaer Aikedai, Weiwei Liao, Yuting Wei, Xinyu Zeng, Kun Qian, Qihang Ding, Lu Yang, Zhen Cheng and Kaipei Luo

Biomaterials, 2026, 328, 123908
DOI: 10.1016/j.biomaterials.2025.123908

Cationic Nano Single Crystals: From In Situ Structural Determination to Synergistic Photoimmunotherapy

Peijuan Zhang, Qifei Shen, Diming Xu, Jianye Yang, Xuwei Luo, Pei Zhou, Jiahui Wang, Yanzi Xu, Lingjie Meng and Dongfeng Dang

J. Am. Chem. Soc., 2025, 147, 41973
DOI: 10.1021/jacs.5c15153

Molecular Engineering of Porphyrins for Near-Infrared Bioimaging and Phototherapy

Chulin Qu, Fan Wu and Zhen Shen

Chemical & Biomedical Imaging, 2026, 4, 737
DOI: 10.1021/cbmi.5c00214

The Current State of Research in the Field of Photosensitizers and Photoactivators for Photodynamic/Photothermal Cancer Therapy: A Review

Pavel Yudaev, Yulia Aleksandrova, Elena Chugunova and Margarita Neganova

IJMS, 2025, 26, 10733
DOI: 10.3390/ijms262110733

Prostate-specific membrane antigen targeted organic semiconducting polymer nanoparticles for enhanced photothermal therapy of prostate cancer

Zhongji Jiang, Xun Zhang, Gaohaer Kadeerhan, Jin Zhang, Jiali Jin, Weijing Hu, Wenmin Guo, Hong Guo and Dongwen Wang

Front. Immunol., 2026, 16
DOI: 10.3389/fimmu.2025.1688048

Growth of NIR-II-Responsive Gold Nanobipyramids with Improved Yield and a Study of Their Application in Cancer Therapy

Yujie Ma, Liangbin Xiong, Wenbin Qiu, Zhixin Dong, Xindong Wei, Jilei Li, Yi Fu, Jie Xiong and Hailong Wu

Langmuir, 2025, 41, 10841
DOI: 10.1021/acs.langmuir.4c05267

Light-controlled pyroptosis via redox-responsive microneedles enhances photodynamic–epigenetic immunotherapy in breast cancer

Hang Yu, Yiqing Chen, Jinjin Yin, Zhongwen Yuan, Senling Feng, Yanrong Duan, Pengke Yan, Shengyao Liu and Wenting Zhu

Materials Today Bio, 2025, 34, 102158
DOI: 10.1016/j.mtbio.2025.102158

Immunotherapy augmentation through photothermal nanomaterial-mediated tumor microenvironment modulation

Zixin Zhao, Yilang He, Chengyu Shi, Jie Li, Qiao Liu, Yuting Zhong, Jing Zhong, Tan Li, Yiyi Deng, Xingyu Zhang, Nengyong Wang and Yuetao Zhao

Coordination Chemistry Reviews, 2026, 547, 217118
DOI: 10.1016/j.ccr.2025.217118

Recent advances in near-infrared fluorescent ligands as a novel frontier in combating antibiotic-resistant bacteria

Wen-De Zheng, Yao-Xun Zeng, Ze-Xin Chen, Jia-Peng Dong, Ying-Ying Zheng and Wing-Leung Wong

Drug Resistance Updates, 2026, 86, 101382
DOI: 10.1016/j.drup.2026.101382

Engineered copper-doped gold nanoclusters supported ROS prolongation for enhanced photodynamic therapy

Xin Xia, Shihong Wu, Hang Zhao and Ronghui Zhou

Materials & Design, 2025, 256, 114287
DOI: 10.1016/j.matdes.2025.114287

Recent advances in nanomaterials for integrated phototherapy and immunotherapy

Zhuqing Sun, Nannan Wang, Yelin Wu, Shihui Wen and Dayong Jin

Coordination Chemistry Reviews, 2025, 535, 216608
DOI: 10.1016/j.ccr.2025.216608

Copper and Iron‐Based Metal‐Organic Frameworks for Synergistic Cancer Phototherapies: Recent Advances, Challenges, and Future Prospects

Kayalvizhi Samuvel Muthiah, Kalaiarasu Lakshminarayanan, Yu Chien Lin, Udesh Dhawan, Loganathan Rangasamy and Ren‐Jei Chung

Advanced Therapeutics, 2025, 8
DOI: 10.1002/adtp.202500117

An all-in-one programmable Janus membrane with gemini AIE surfactant for integrated bioaerosol management

Saisai Yan, Xiyao Wang, Zishu Wen, Yufeng Guan, Bixiao Cao, Xuanzhe Wang, Ning Du, Yingjie Zhong, Ningning He, Shangyong Li and Peng Sun

Chemical Engineering Journal, 2026, 530, 173341
DOI: 10.1016/j.cej.2026.173341

Advanced Anti‐Counterfeiting: Integrating Humidity‐Responsive Room‐Temperature Phosphorescence and Chromism in Biomass Supramolecular Frameworks

Xin Jin, Shuai Wang, Jing Bian, Feng Peng and Ming‐Fei Li

Adv Funct Materials, 2026, 36
DOI: 10.1002/adfm.202516635

Nanoparticles-based phototherapy systems: molecular mechanisms and clinical applications

Deepak S. Chauhan, Rajendra Prasad, Mukesh Dhanka, Navneet Kaur, Hitasha Vithalani, Kaveesha Liyanapathirana, Roopa Hebbandi Nanjundappa, Huile Gao and Channakeshava Sokke Umeshappa

Sig Transduct Target Ther, 2026, 11
DOI: 10.1038/s41392-025-02536-w