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Gastrodia elata Polysaccharide Ameliorates Parkinson’s Disease by Enhancing Dopamine Levels, Inhibiting NLRP3 Inflammasome Activation, and Promoting Mitochondrial Autophagy

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From gut to whole body: Natural polysaccharide-based multi-axis network strategies for systemic disease adjuvant therapy

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Plant polysaccharides in neuroprotection: mechanistic insights across central nervous system disorders

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Front. Pharmacol., 2026, 16
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Butyrate-Modified Hyaluronic Acid Ameliorates MPTP-Induced Parkinson’s Disease via Modulating PINK1/Parkin-Involved Mitophagy and Intestinal Flora

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A comprehensive review on structural, chemical, and functional perspectives of dietary polysaccharide-driven gut microbiota modulation: Mechanisms and challenges

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Xifeng Jiannao pill mitigates MPTP-induced neuronal apoptosis by reducing inflammation and oxidative stress via MAPK signaling

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Induced Pluripotent Stem Cells Derived Cellular Models for Investigating Parkinson’s Disease Pathogenesis and Drug Screening

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Advances in polysaccharides from traditional Chinese medicine for the treatment of central nervous system disorders: A comprehensive review

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The food and medicine homologous Chinese Medicine from Leguminosae species: A comprehensive review on bioactive constituents with neuroprotective effects on nervous system

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Effects of traditional Chinese medicine polysaccharides on chronic diseases by modulating gut microbiota: A review

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Advances in natural medicinal plant-based interventions against hypoxia-related neuroinflammation

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Clonostachys rosea, a Pathogen of Brown Rot in Gastrodia elata in China

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Structure-activity relationships and mechanisms of natural polysaccharides in modulating neurological disorders via the microbiota-gut-brain axis

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Analysis methods and food application of Gastrodia elata and related products: A review

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Polysaccharide-driven quality control of Gastrodia elata Blume: A multidimensional strategy integrating LC-MS/MS-based quantitative analysis, machine learning, and anti-neuroinflammatory bioactivity

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Convergence of Neuroinflammation, Microbiota, and Parkinson’s Disease: Therapeutic Insights and Prospects

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Exploring the potential protective mechanism of Gastrodia elata Blume in Parkinson's disease using LC-MS/MS-based striatal metabolomics

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A Gastrodia elata polysaccharide for restoring intestinal immunocompromise

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Deep eutectic solvent extraction of polysaccharides from Gastrodiae elata with ultrasonic and enzymes assistance: Process optimization, structure, and antioxidant activity

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Natural Products from Chinese Medicine Targeting NF-κB Signaling: Emerging Therapeutic Avenues for Neurodegenerative Diseases

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Research on Antioxidant Activity of Phenolic Compounds from Bistorta Vivipara L. Achenes Based on Solid-Phase Extraction Coupled with On-Line Ferric Ion Reducing Antioxidant Potential–High-Performance Liquid Chromatography (FRAP–HPLC)

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Gut bacteria composition in animal models of Parkinson’s disease: a systematic review and meta-analysis

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Ultrasound-Assisted Enzymatic Extraction of Polysaccharides from Tricholoma matsutake: Optimization, Structural Characterization, and Inhibition of α-Synuclein Aggregation

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Identification of novel phenolic inhibitors from traditional Chinese medicine against toxic α-synuclein aggregation via regulating phase separation

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Ginsenoside Re exerts neuroprotective in MPTP mice: potential links to gut microbiota and serum metabolism

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Preparation and evaluation of gastrodin microsphere-loaded Gastrodia elata polysaccharides composite hydrogel on UVB-induced skin damage in vitro and in vivo

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Research progress on natural products in regulating the gut microbiota in Parkinson’s disease

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Extraction, purification, characteristics, bioactivities, application, and toxicity of Gastrodia R. Br. polysaccharides: A review

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Bioactive compounds from Chinese herbal plants for neurological health: mechanisms, pathways, and functional food applications

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The role of the gut microbiota in neuropsychiatric disorders and therapy

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Natural mannose-containing glycans as gut modulators: A mechanistic and translational perspective

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Difructose anhydrides from inulin enhance cognitive function via gut microbiota modulation and synaptic signaling in mice

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Ulva polysaccharide alleviates Parkinson's disease by regulating inflammation, oxidative damage, and gut microbiota

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Chinese Herbal Medicine Targets Gut Microbiota to Combat Neurodegenerative Diseases: Potential Mechanisms and Clinical Implications

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The interplay between gut microbiota and the brain-gut axis in Parkinson’s disease treatment

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Polysaccharides Extraction from Opuntia milpa alta and Their Protective Effect on Alcohol-Induced Neuro 2a Cell Damage via Ferroptosis

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Digestive characteristics of Gastrodia elata Blume polysaccharide and related impacts on human gut microbiota in vitro

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Gastrodia elata polysaccharides: A comprehensive review of extraction, purification, characterization, structure-activity relationship and quality control applications

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Protective effect of ginsenoside CK against MPTP-induced Parkinson’ s disease mouse model by suppressing oxidative stress and inflammation, and modulating the gut microbiota

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Herbal Interventions in Parkinson’s Disease: A Systematic Review of Preclinical Studies

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Antioxidant and Anti-Inflammatory Effects of Crude Gastrodia elata Polysaccharides in UVB-Induced Acute Skin Damage

Jiajia Liu, Xiaoqi Yang, Xing Huang, Yuan Luo, Qilin Zhang, Feng Wang, Yicen Lin and Lianbing Lin

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Advances in natural polysaccharides in Alzheimer's disease and Parkinson's disease: Insights from the brain-gut axis

Yueqin Feng and Fengjin Hao

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Pharmacological mechanisms of puerarin in the treatment of Parkinson's disease: An overview

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Fucoidan ameliorates rotenone-induced Parkinsonism in mice by regulating the microbiota-gut-brain axis

Xiaojing Yang, Xuan Zhang, Yufang Ma, Sheng Li, Qingshan Wang, Jau-Shyong Hong, Guangli Yu, Bing Qi, Jie Wang, Chengkang Liu, Qingsen Shang, Xuefei Wu and Jie Zhao

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