(E)-2-Methoxyethene-1-sulfonyl fluoride as a precursor of acetylene for synthesis of C1/C2 non-functionalized pyrrolo[2,1-a]isoquinoline derivatives

Jiahong Ma, Weikang Lin and Hua-Li Qin

New J. Chem., 2023, 47, 16332
DOI: 10.1039/D3NJ03325B

Diversely functionalized isoquinolines and their core-embedded heterocyclic frameworks: a privileged scaffold for medicinal chemistry

Archana Vijayakumar, M. Manod, R. Bharath Krishna, Abra Mathew and Chithra Mohan

RSC Med. Chem., 2023, 14, 2509
DOI: 10.1039/D3MD00248A

Total synthesis of lamellarin G trimethyl ether through enaminone cyclocondensation

Urtė Šachlevičiūtė, Neringa Kleizienė, Aurimas Bieliauskas, Algirdas Šačkus and Till Opatz

Org. Biomol. Chem., 2023, 21, 5997
DOI: 10.1039/D3OB00870C

One-pot C–N/C–C bond formation and oxidation of donor–acceptor cyclopropanes with tetrahydroisoquinolines: access to benzo-fused indolizines

Pallab Karjee, Bijoy Debnath, Santu Mandal, Sharajit Saha and Tharmalingam Punniyamurthy

Chem. Commun., 2024, 60, 4068
DOI: 10.1039/D4CC00810C

Photo- and electro-chemical synthesis of substituted pyrroles

Binbin Huang

Green Chem., 2024, 26, 11773
DOI: 10.1039/D4GC04495A

Chiral π–Cu(ii)-catalyzed site-, exo/endo-, and enantioselective dearomative (3 + 2) cycloadditions of isoquinolinium ylides with enamides, dienamides, and a trienamide

Weiwei Guo, Jianhao Huang and Kazuaki Ishihara

Chem. Sci., 2024, 15, 10926
DOI: 10.1039/D4SC02946A

Aerobic oxidative C–C bond formation through C–H bond activation catalysed by flavin and iodine

Hazuki Miyake, Nico Ishige, Hayaki Okai and Hiroki Iida

Org. Biomol. Chem., 2024, 22, 7736
DOI: 10.1039/D4OB01317D

A dual-engineered covalent organic framework with charge-oxygen synergy promotes photocatalytic dipolar [3 + 2] cycloaddition

Yuemeng Liu, Lifan Shen, Hao Yang, Xiaojia Zhao and Xingwang Lan

Chem. Sci., 2025, 16, 17827
DOI: 10.1039/D5SC04639D

Synthesis of mono-fluorinated heterocycles with a ring-junction nitrogen atom via Rh(iii)-catalyzed CF3-carbenoid C–H functionalization and defluorinative annulation

Haosheng Li, Mingjing Mei, Duozhi Wang and Lei Zhou

Org. Chem. Front., 2023, 10, 1544
DOI: 10.1039/D2QO02008D

Photo-induced tungsten-catalyzed cascade synthesis of pyrrolo[2,1-a]isoquinoline-1,3-dicarboxylate and its reaction mechanism

Yongshun Wen, Hong-Xian Jin, Yan-Hua Qiu, Yingtong Zong, Wenjun Luo, Zhengwang Chen and Daohong Yu

Chem. Commun., 2024, 60, 4573
DOI: 10.1039/D4CC00169A

tert-Butyl nitrite as a privileged reagent for a C–H bond (sub)nitration reaction in organic synthesis

Jiaoli Ma, Pinzhu Chen, Junli Zeng, Penghu Guo and Huicheng Cheng

New J. Chem., 2024, 48, 14128
DOI: 10.1039/D4NJ01802H

Recent advances in the synthesis of chromenone fused pyrrolo[2,1-a]isoquinoline derivatives

Sonali Bera, Avishek Maji, Susanta Patra, Dibyendu Sekhar Mahanty, Shubhankar Samanta, Swarna Kamal Samanta, Biplab Biswas and Prasanta Patra

New J. Chem., 2023, 47, 22246
DOI: 10.1039/D3NJ03713D

Metal-free photoinduced alkylative [3 + 2] annulation of terminal alkynes with N-alkyl isoquinolin-2-iums by catalytic isoquinoline-based electron donor–acceptor complex

Ya-Fei Han, Yang Li, Xuan-Hui Ouyang, Ming Hu, Jing-Hao Qin, Ze Tan and Jin-Heng Li

Org. Chem. Front., 2023, 10, 1173
DOI: 10.1039/D2QO01754G

Organocatalytic regio- and enantioselective C1-arylation of β,γ-alkynyl-α-imino esters with pyrrolo[2,1-a]isoquinolines

Xuan Zhang, Xiaoxiao Song and Qijian Ni

Chem. Commun., 2024, 60, 831
DOI: 10.1039/D3CC04946A

CuI-Catalyzed Selenylation of Pyrrolo[2,1-a]isoquinolines and Other Electron-Rich Heteroarenes

Jing Zhou, Jia-Yi Han, Xin Yu, Liu Yang, Man Jiang, Yun-Meng Li and Hai-Lei Cui

J. Org. Chem., 2024, 89, 14050
DOI: 10.1021/acs.joc.4c01462

Tandem Isomerization/α,β-Site-Selective and Enantioselective Addition Reactions of N-(3-Butynoyl)-3,5-dimethylpyrazole Induced by Chiral π–Cu(II) Catalysts

Weiwei Guo, Masahiro Hori, Yoshihiro Ogura, Kazuki Nishimura, Kosuke Oki, Tomoyuki Ikai, Eiji Yashima and Kazuaki Ishihara

J. Am. Chem. Soc., 2023, 145, 27080
DOI: 10.1021/jacs.3c10820

Synthesis of Hexahydropyrrolo-isoquinolines by 1,3-Dipolar cycloaddition of tetrahydroisoquinolines and cinnamaldehydes

You-Gui Li, Wei-Ke Chen, You-Qiang Guo, Zhang Zhu, Jing-Jing Cao, Zhen-Yu Wang and Xiang Wu

Tetrahedron Letters, 2023, 122, 154519
DOI: 10.1016/j.tetlet.2023.154519

TBHP/Et3N-Promoted Chemoselective Formylation and Peroxidation of Pyrrolo[2,1-a]isoquinolines

Xiang Huang, Jing Zhou, Shu-Chen Pei and Hai-Lei Cui

J. Org. Chem., 2024, 89, 6353
DOI: 10.1021/acs.joc.4c00321

Titanium-Mediated aza-Nazarov Annulation for the Synthesis of N-Fused Tricycles: A General Method to Access Lamellarin Analogues

Zhixin Liu, Xinyu Liu, Shengkuan Yang, Xiaohe Miao, Dehai Li and De Wang

J. Org. Chem., 2022, 87, 10319
DOI: 10.1021/acs.joc.2c01379

Modification of Pyrrolo[2,1‐a]isoquinolines through Iron‐Catalyzed Aminomethylenation with Amines and Dimethyl Sulfoxide

Xiao‐Hui Chen and Hai‐Lei Cui

Eur J Org Chem, 2022, 2022
DOI: 10.1002/ejoc.202200807

Synthesis of Pyrrolo [2,1-a]isoquinolines using Cu NPs decorated microcrystalline cellulose in 2-Methyl-THF: A biodegradable heteregeneous nanocatalyst for the sustainable cascade approach

Pranav S. Shrivastav, Nandish Talpada, Anuj S. Sharma, Vinay S. Sharma, Rahul Ahmed, Achalkumar Ammathnadu Sudhakar and Rajender S. Varma

Molecular Catalysis, 2024, 569, 114569
DOI: 10.1016/j.mcat.2024.114569

Base‐Promoted Homolytic Aromatic Substitution (BHAS) Reactions and Hydrodehalogenations Driven by Green Light and an Iron(III)‐NHC Photoredox Catalyst

Lisa H. M. de Groot, Clara García‐Mateos, Catherine E. Johnson, Valtýr Freyr Hlynsson, Alpesh K. Sharma, Reiner Lomoth and Kenneth Wärnmark

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202500409

Copper-catalyzed synthesis of pyrrolo[2,1-a]isoquinolines through condensation/cycloaddition/aromatization cascade

Man Jiang, Xue Sheng, Yu Luo and Hai-Lei Cui

Tetrahedron Letters, 2025, 173, 155829
DOI: 10.1016/j.tetlet.2025.155829

Recent advances in the design and synthesis of coumarins and their derivatives via Suzuki–Miyaura reaction (2002–2024)

Khokan Samanta, Sarmistha Adak, Sujan Samanta, Susanta Patra and Prasanta Patra

Monatsh Chem, 2025, 156, 1239
DOI: 10.1007/s00706-025-03396-4

HCl/DMSO/HFIP-Mediated Chlorination of Pyrrolo[2,1-a]isoquinolines and Other Electron-Rich Heteroarenes

Jing Zhou, Xiang Huang, Xin Yu, Liu Yang, Jia-Yi Han, Tsesong Lhazom and Hai-Lei Cui

J. Org. Chem., 2024, 89, 9789
DOI: 10.1021/acs.joc.4c00151

Metal‐Free [3 + 3] and [4 + 2] Cascade Cyclization of Dihydroisoquinolines and Ene‐Yne‐Oxazolones: Synthesis of Indenoisoquinolinoquinolinamides

Rattana Worayuthakarn, Phum Tachachartvanich, Rapeepat Sangsuwan, Somsak Ruchirawat and Nopporn Thasana

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202502380

Photoinduced α‐Alkylation of Tetrahydroisoquinolines with Organoboron Reagent Enabled by Organic Photocatalyst

Pu Wang, Ke Meng, Shi‐Huan Guo, Meng‐Yue Wang, Ya‐Ru Gao and Yong‐Qiang Wang

Eur J Org Chem, 2023, 26
DOI: 10.1002/ejoc.202201157

NH4OAc/DMSO-Promoted Benzylation of Pyrrolo[2,1-a]isoquinolines

Xiao-Hui Chen, Tsesong Lhazom and Hai-Lei Cui

J. Org. Chem., 2023, 88, 13598
DOI: 10.1021/acs.joc.3c01302

Synthesis of Furan-Containing Pyrrolo[2,1-a]Isoquinoline Derivatives Based on Phosphoranylidenesucciminide

G. F. Sakhautdinova, I. M. Sakhautdinov and A. G. Mustafin

Chem Nat Compd, 2025, 61, 335
DOI: 10.1007/s10600-025-04642-1

Modification of Pyrrolo[2,1-a]isoquinolines and Polysubstituted Pyrroles via Methylenation with Acetyl Chloride and Dimethylsulfoxide

Wan-Zhen Li, Wei Zhang, Xiao-Hui Chen, Zhao-Dong Wang and Hai-Lei Cui

J. Org. Chem., 2022, 87, 11491
DOI: 10.1021/acs.joc.2c01090

Iron-catalyzed dimerization of pyrrolo[2,1-a]isoquinolines and pyrrolo[1,2-a]quinolines

Xiang Huang, Wan-Zhen Li, Shu-Chen Pei and Hai-Lei Cui

Tetrahedron Letters, 2023, 126, 154657
DOI: 10.1016/j.tetlet.2023.154657

HBr/TMSO/HFIP Mediated Chemoselective Modifications of Pyrrolo[2,1‐a]Isoquinolines

Yun‐Meng Li, Man Jiang, Jing Zhou and Hai‐Lei Cui

Asian J Org Chem, 2024, 13
DOI: 10.1002/ajoc.202400323

Progress in N-α-C(sp3)—H Bond Functionalization for the Synthesis of N-Heterocycles

Yulan Fan, Xiaoying Zou, Xiaoqing Zhu, Lüyin Zheng and Wei Guo

Chinese Journal of Organic Chemistry, 2025, 45, 1047
DOI: 10.6023/cjoc202408019

Fullerene C70 as Photoredox Catalyst for the Synthesis of Pyrrolo[2,1‐a]isoquinolines by 1,3‐Dipolar Cycloaddition‐Aromatization Sequence

Priksha Rana, Ganesh Udari, Balasubramanian Sridhar and Surya Prakash Singh

Chemistry A European J, 2023, 29
DOI: 10.1002/chem.202203354

AcBr/DMSO Mediated Sulfenylation of Pyrrolo[2,1-a]isoquinolines

Xiao-Hui Chen and Hai-Lei Cui

J. Org. Chem., 2023, 88, 7347
DOI: 10.1021/acs.joc.3c00566

Copper-Catalyzed Synthesis of Pyrrolo[1,2-c]quinazolines and Pyrrolo[2,1-a]isoquinolines and Antiplasmodial Evaluation

Natália M. Moreira, Ingrid T. de Miranda, Jhonathan R. N. dos Santos, Till Opatz, Glaucius Oliva, Rafael V. C. Guido and Arlene G. Corrêa

J. Org. Chem., 2023, 88, 8781
DOI: 10.1021/acs.joc.3c00616

Catalyst‐Free (3 + 2) Annulation of Morita–Baylis–Hillman Carbonates With Isoquinolines to Access Functionalized Pyrrolo[2,1‐a]Isoquinolines

Na‐Na Zhao, Ya‐Fei Li, Yue‐Yao Ma, Xiao‐Ran Wang, Yu Tang, Kai‐Kai Wang and Aili Sun

Journal of Heterocyclic Chem, 2025, 62, 1358
DOI: 10.1002/jhet.70080

Bromide/sulfoxide-promoted dearomative construction of indolizino[8,7-b]indoles

Jing Zhou, Man Jiang, Yu Luo and Hai-Lei Cui

Tetrahedron, 2026, 189, 135019
DOI: 10.1016/j.tet.2025.135019

POCl3/Sulfoxide and AcCl/Sulfoxide Mediated Chlorination of Pyrrolo[2,1-a]isoquinolines

Hai-Lei Cui and Xiao-Hui Chen

J. Org. Chem., 2023, 88, 11935
DOI: 10.1021/acs.joc.3c01200

Bromination of Pyrrolo[2,1-a]isoquinolines with Acetyl Bromide and Dimethyl Sulfoxide

Hai-Lei Cui

J. Org. Chem., 2023, 88, 2822
DOI: 10.1021/acs.joc.2c02484

Cascade Synthesis of Pyrrolo[1,2-a]quinolines and Pyrrolo[2,1-a]isoquinolines via Formal [3 + 2]-Cycloaddition of Push–Pull Nitro Heterocycles with Carbonyl-Stabilized Quinolinium/Isoquinolinium Ylides

Dmitry V. Osipov, Maxim R. Demidov, Alina A. Artemenko, Daria A. Rashchepkina, Pavel E. Krasnikov and Vitaly A. Osyanin

J. Org. Chem., 2024, 89, 9816
DOI: 10.1021/acs.joc.4c00455

Solvent-Controlled Diastereodivergent Synthesis of Hexahydropyrrolo[2,1-a]isoquinolines through Pd/C-Catalyzed Dehydrogenative [3 + 2] Cycloaddition

Ji-Chao Lu, Hao Bai, Yue-He Huang, Zhen-Yu Wang, Lan-Jun Cheng, You-Gui Li and Xiang Wu

J. Org. Chem., 2024, 89, 18723
DOI: 10.1021/acs.joc.4c02343

Nitration of Pyrrolo[2,1‐a]isoquinolines with NaNO2/HFIP

Xiang Huang, Yun‐Meng Li, Jing Zhou, Yu‐Yi Pan, Wei Li, Xiao‐Hui Chen, Xin Yu, Shu‐Chen Pei and Hai‐Lei Cui

Eur J Org Chem, 2024, 27
DOI: 10.1002/ejoc.202400116

Modification of Pyrroloisoquinolines with 2‐Bromoketones and Dimethyl Sulfoxide through Bromination

Xiao‐Hui Chen, Wan‐Zhen Li, Wei Zhang, Zhao‐Dong Wang and Hai‐Lei Cui

Asian J Org Chem, 2022, 11
DOI: 10.1002/ajoc.202200342

Photoinduced Radical Annulations of Tetrahydroisoquinoline Derivatives with 2-Benzothiazolimines: Highly Diastereoselective Synthesis of Fused Hexahydroimidazo[2,1-a]isoquinolines

Bing Yi, Wenhui Zhang, Zi-Qi Yi, Fei Chen, Qianqian Zeng, Niannian Yi, Li Lv, Fan Zhang, Yanjun Xie and Jian-Ping Tan

J. Org. Chem., 2024, 89, 13491
DOI: 10.1021/acs.joc.4c01691

Recent Advances in Synthetic Isoquinoline-Based Derivatives in Drug Design

Łukasz Balewski and Anita Kornicka

Molecules, 2025, 30, 4760
DOI: 10.3390/molecules30244760

An Overview on the Synthesis of Lamellarins and Related Compounds with Biological Interest

Vasiliki-Panagiota M. Mitsiou, Anastasia-Maria N. Antonaki, Matina D. Douka and Konstantinos E. Litinas

Molecules, 2024, 29, 4032
DOI: 10.3390/molecules29174032

An Overview of the Synthesis of 3,4-Fused Pyrrolocoumarins of Biological Interest

Eleni Kapidou and Konstantinos E. Litinas

Molecules, 2024, 29, 2748
DOI: 10.3390/molecules29122748

Iron-Catalyzed Synthesis of Pyrrolo[2,1-a]isoquinolines via 1,3-Dipolar Cycloaddition/Elimination/Aromatization Cascade and Modifications

Xiao-Hui Chen, Yu-Yi Pan, Wei-Xun Wang and Hai-Lei Cui

Synlett, 2022, 33, 1645
DOI: 10.1055/a-1896-3512

Nitration of Pyrrolo[2,1-a]isoquinolines

Xiao-Hui Chen, Dan-Dan Ma, Xin Gao, Yun-Meng Li, Da-Bo Jiang, Chao Ma and Hai-Lei Cui

J. Org. Chem., 2023, 88, 4649
DOI: 10.1021/acs.joc.3c00125

Synthesis of Fluorinated Pyrrolo[2,1-a]isoquinolines through Decarboxylative/Dehydrofluorinative [3 + 2] Cycloaddition Aromatization of Isoquinolinium N-Ylides with Difluoroenoxysilanes

Wenxue Xi, Yiheng Zhang, Haijian Wu, Jinshan Li, Yurong Wang, Jianguo Yang, Zhiming Wang and Weijun Yao

Org. Lett., 2023, 25, 4908
DOI: 10.1021/acs.orglett.3c01728

Stereoselective Synthesis of Biology-Oriented Pentacyclic Pyrrolo[2,1-a]isoquinoline Scaffolds by Photoredox-Induced Radical Annulations

Zi-Qi Yi, Wenhui Zhang, Bing Yi, Chang Liu, Yanjun Xie, Maoqing Li, Yi Xiong, Weidong Wu and Jian-Ping Tan

Org. Lett., 2025, 27, 2197
DOI: 10.1021/acs.orglett.5c00277

Green and Efficient Construction of Chromeno[3,4-c]pyrrole Core via Barton–Zard Reaction from 3-Nitro-2H-chromenes and Ethyl Isocyanoacetate

Ivan A. Kochnev, Alexey Y. Barkov, Nikolay S. Zimnitskiy, Vladislav Y. Korotaev and Vyacheslav Y. Sosnovskikh

Molecules, 2022, 27, 8456
DOI: 10.3390/molecules27238456

Modular Assembly of Pyrrolo[3,4-c]isoquinolines through Rh-Catalyzed Cascade C–H Activation/Annulation of O-Methyl Aryloximes with Maleimides

Yinsong Wu, Yanan Liu, Yangzilin Kong, Mengdi Wu, Demao Wang, Yongjia Shang and Xinwei He

J. Org. Chem., 2024, 89, 8447
DOI: 10.1021/acs.joc.4c00324

Sulfoxide-Controlled Chlorination of Pyrrolo[2,1-a]isoquinoline with Acetyl Chloride

Man Jiang, Jing Zhou and Hai-Lei Cui

J. Org. Chem., 2025, 90, 10994
DOI: 10.1021/acs.joc.5c01386

Enriching pyrrole components in bio-oil by nitrogen-rich pyrolysis of tobacco stem employing ZIF-67/ZSM-5 dual-catalyst

Xiaoyu Song, Shanjian Liu, Tianhao Li, Hui Wang, Fupeng Huang, Xueyuan Bai and Dongmei Bi

Journal of Analytical and Applied Pyrolysis, 2025, 191, 107212
DOI: 10.1016/j.jaap.2025.107212

Synthesis of pyrrolo[2,1-a]isoquinoline-derived diheteroaryl sulfides through Na2S2O3/DMSO/HI-based sulfenylation

Man Jiang, Jing Zhou, Yu Luo, Zi-ming Wan, Ying Li and Hai-Lei Cui

Tetrahedron, 2026, 196, 135273
DOI: 10.1016/j.tet.2026.135273

Enantiodivergent Synthesis of (+)- and (–)-Crispine A

Yanben Wang, Zuming Lin, Sha-Hua Huang, Lili Zhu and Ran Hong

Chinese Journal of Organic Chemistry, 2025, 45, 1021
DOI: 10.6023/cjoc202406048

Synthesis of Pyrrolo[2,1-a]isoquinolines through Cu-Catalyzed Condensation/Addition/Oxidation/Cyclization Cascade

Hai-Lei Cui and Xiao-Hui Chen

J. Org. Chem., 2022, 87, 15435
DOI: 10.1021/acs.joc.2c01978

TfOH-Catalyzed Synthesis of Bis(pyrrolo[2,1-a]isoquinolinyl) methanes

Jing Zhou, Xue Sheng, Yu-Yi Pan and Hai-Lei Cui

Synlett, 2025, 36, 1079
DOI: 10.1055/a-2460-8054

HI/DMSO-Based Chemoselective Oxidative Halogenation of Pyrrolo[2,1-a]isoquinolines

Hai-Lei Cui

Synlett, 2025, 36, 1223
DOI: 10.1055/a-2508-2171

Pd/C-Catalyzed Dehydrogenative [3 + 2] Cycloaddition for the Synthesis of Dihydropyrrolo[2,1-a]isoquinolines

You-Gui Li, Ji-Chao Lu, Meng-Cheng Wang, Bo Wu, Shi-Ke She and Xiang Wu

J. Org. Chem., 2025, 90, 7995
DOI: 10.1021/acs.joc.5c00904

Photocatalytic Oxidative [3+2] Cycloaddition for Pyrrolo[2,1‐a]isoquinoline Synthesis Using a Porphyrin‐Based Covalent Organic Framework

Cheng‐Juan Wu, Ming‐Zhen Shao, Li‐Jing Niu, Ting‐Rui Li, Wen‐Jing Liang, Jing‐Lan Kan, Yan Geng and Yu‐Bin Dong

Eur J Org Chem, 2023, 26
DOI: 10.1002/ejoc.202300232

Iron-Catalyzed Synthesis of Peroxylpyrrolo[2,1-a]isoquinolines through Oxidative Dearomatization

Xiang Huang, An-Ni Yu, De Yang, Xin Gao, Shu-Ting Liang, Shu-Chen Pei and Hai-Lei Cui

J. Org. Chem., 2023, 88, 15326
DOI: 10.1021/acs.joc.3c01824

Base-Mediated Cascade Lactonization/1,3-Dipolar Cycloaddition Pathway for the One-Pot Assembly of Coumarin-Functionalized Pyrrolo[2,1-a]isoquinolines

Qiang Tang, Yanan Liu, BinBin Fei, Qianqian Tao, Chen Wang, Xiaochun Jiang, Xinwei He and Yongjia Shang

J. Org. Chem., 2024, 89, 8420
DOI: 10.1021/acs.joc.4c00239

Synthesis of Multifused Pyrrolo[1,2-a]quinoline Systems by Tandem Aza-Michael–Aldol Reactions and Their Application to Molecular Sensing Studies

Anirban Bera, Sk Abulkalam Azad, Prasanta Patra, Nayim Sepay, Rathin Jana, Tapas Das, Amit Saha and Shubhankar Samanta

J. Org. Chem., 2023, 88, 5622
DOI: 10.1021/acs.joc.3c00109

Metal‐Free Electrochemical [3+2] Cycloaddition between α‐Amino Carbonyls and Tosylmethyl Isocyanide en route to Substituted Imidazoles

Samrat Mallick, Mrinmay Baidya and Suman De Sarkar

Adv Synth Catal, 2024, 366, 241
DOI: 10.1002/adsc.202301071

Synthesis of 1,3-diaryl-5,6-dihydropyrrolo[2,1-a] isoquinolines via copper-promoted reaction of tetrahydroisoquinolines with α,β-unsaturated ketones under solvent-free conditions

Huacan Xu, Ke Zhang, Linglong Zhang, Yanjing Zhang, Jinwei Sun, Yuling Li and Yun Liu

Tetrahedron, 2026, 194, 135178
DOI: 10.1016/j.tet.2026.135178

Asymmetric Double Oxidative [3 + 2] Cycloaddition for the Synthesis of CF3-Containing Spiro[pyrrolidin-3,2′-oxindole]

Tao Wang, Wen-Bin Wang, Yan-Ming Fu, Cheng-Feng Zhu, Lan-Jun Cheng, Yang-En You, Xiang Wu and You-Gui Li

Org. Lett., 2023, 25, 3152
DOI: 10.1021/acs.orglett.3c01083

Synthesis of Densely Functionalized Pyrroles via Photoinduced C-Insertion into N-Alkylenamines: Sequential C(sp2)–H/C(sp3)–H Activation with Bromine Radicals

Chuan-Hua Qu, Su-Ya Liu, Shan-Shan Chen, Nian Wang, Ying Cheng, Shi-You Xue, Xue-Ying Yang, Wen-Bin Zong, Yuan Zhou, Li-Min Zhang, Xiang-Yi Zeng, Qin-Mao Li, Lan-Bin He, Xiao Yan and Gui-Ting Song

Org. Lett., 2025, 27, 11264
DOI: 10.1021/acs.orglett.5c03559

Highly regio- and diastereoselective synthesis of spiropyrrolidine-fused pyrrolo[2,1-a]isoquinolines through dearomative (3 + 2) cycloaddition reactions

Kai-Kai Wang, Liang-Man Wu, Bo-Wen Zhang, Yi-Fan Zhang, Yu Tang, Si-Qi Wei, Yan-Rui Ma, Guo-Yi Yan and Rongxiang Chen

Tetrahedron, 2026, 193, 135155
DOI: 10.1016/j.tet.2026.135155

Iron‐catalyzed oxidative [3+2] cycloaddition‐aromatization cascade: Synthesis of pyrrolo‐[2,1‐a]isoquinolines

Wen Jing Hu, Na na Liu and Abudureheman Wusiman

Journal of Heterocyclic Chem, 2023, 60, 1633
DOI: 10.1002/jhet.4669

Oxidative Iodination of Pyrrolo[2,1-a]isoquinolines with NaI/mCPBA

Hai-Lei Cui

J. Org. Chem., 2025, 90, 7947
DOI: 10.1021/acs.joc.5c00386

Chemistry of Quinolines and their Agrochemical Potential

Divya Utreja, Riddhi Salotra, Gurbir Kaur, Shivali Sharma and Sonia Kaushal

COC, 2023, 26, 1895
DOI: 10.2174/1385272827666221219101902