Issue 8, 2019

The impact of nanoparticle shape on cellular internalisation and transport: what do the different analysis methods tell us?

Abstract

This article focuses on how nanoparticle shape affects the cellular internalisation and transport of nanoparticles inside cells and what the different analytical methods for determining nanoparticle internalisation by cells tell us. Rod-shaped nanoparticles typically show greater cellular internalisation relative to spherical nanoparticles, although there are studies with contradictory conclusions. The contradiction may be a result of differences in the materials being used in the comparison and/or a result of the analytical method employed. Finally, future opportunities in studying cellular internalisation with 3D cell-culture models and light-sheet microscopy are discussed.

Graphical abstract: The impact of nanoparticle shape on cellular internalisation and transport: what do the different analysis methods tell us?

Article information

Article type
Focus
Submitted
29 4月 2019
Accepted
05 7月 2019
First published
06 7月 2019

Mater. Horiz., 2019,6, 1538-1547

The impact of nanoparticle shape on cellular internalisation and transport: what do the different analysis methods tell us?

W. Wang, K. Gaus, R. D. Tilley and J. J. Gooding, Mater. Horiz., 2019, 6, 1538 DOI: 10.1039/C9MH00664H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements