Issue 3, 2017

AIEgen-functionalised mesoporous silica nanoparticles as a FRET donor for monitoring drug delivery

Abstract

Aggregation-induced emission luminogens (AIEgens), tetraphenylethene, were post grafted onto mesoporous silica nanoparticles to form AIEgen-functionalised mesoporous materials. The obtained blue-emitting materials can serve as a fluorescence resonance energy transfer (FRET) donor for monitoring the release process of doxorubicin hydrochloride (DOX) as an acceptor by the change of the fluorescent signal, showing potential application in imaging-guided therapy.

Graphical abstract: AIEgen-functionalised mesoporous silica nanoparticles as a FRET donor for monitoring drug delivery

Supplementary files

Article information

Article type
Research Article
Submitted
07 11月 2016
Accepted
31 12月 2016
First published
03 1月 2017

Inorg. Chem. Front., 2017,4, 468-472

AIEgen-functionalised mesoporous silica nanoparticles as a FRET donor for monitoring drug delivery

D. Wang, J. Chen, L. Ren, Q. Li, D. Li and J. Yu, Inorg. Chem. Front., 2017, 4, 468 DOI: 10.1039/C6QI00488A

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