Issue 6, 2019

Recent advances in transition metal-catalyzed C(sp2)–H nitration

Abstract

Nitroaromatic compounds play an important role in organic synthesis, medicinal chemistry and chemical industry. Among the recently reported synthetic methods to access nitroarenes, transition metal-catalyzed C(sp2)–H activation/nitration has become one of the most attractive protocols, showing high regioselectivity, excellent functional group tolerance and step-economy. In this review, we discuss advances in direct C(sp2)–H nitration for the synthesis of nitroaromatic compounds and mechanistic insights over the past decade. We hope this will provide valuable information for researchers interested in the rapidly developing field of metal-catalyzed C(sp2)–H nitration.

Graphical abstract: Recent advances in transition metal-catalyzed C(sp2)–H nitration

Article information

Article type
Review Article
Submitted
06 11月 2018
Accepted
02 1月 2019
First published
03 1月 2019

Org. Biomol. Chem., 2019,17, 1351-1361

Recent advances in transition metal-catalyzed C(sp2)–H nitration

L. Song, Z. Fan and A. Zhang, Org. Biomol. Chem., 2019, 17, 1351 DOI: 10.1039/C8OB02750A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements