Issue 22, 2018

Recent advances in the application of indoles in multicomponent reactions

Abstract

Indoles are some of the most versatile and common nitrogen-based heterocyclic scaffolds and are frequently used in the synthesis of various organic compounds. Indole based compounds are very important among heterocyclic structures due to their biological and pharmaceutical activities. The last decade, in particular, has witnessed considerable activity towards the synthesis of indole derivatives due to the possibilities for the design of polycyclic structures by the incorporation of multiple fused heterocyclic scaffolds in an attempt to achieve promising new heterocycles with chemical and biomedical relevance. In this study, we provide an overview on recent applications of indole in the multicomponent reactions for the synthesis of various heterocyclic compounds during the period of 2012 to 2017.

Graphical abstract: Recent advances in the application of indoles in multicomponent reactions

Article information

Article type
Review Article
Submitted
13 12月 2017
Accepted
05 3月 2018
First published
28 3月 2018
This article is Open Access
Creative Commons BY license

RSC Adv., 2018,8, 12069-12103

Recent advances in the application of indoles in multicomponent reactions

G. Mohammadi Ziarani, R. Moradi, T. Ahmadi and N. Lashgari, RSC Adv., 2018, 8, 12069 DOI: 10.1039/C7RA13321A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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