Issue 10, 2017

Concise asymmetric total synthesis of (−)-patchouli alcohol

Abstract

The asymmetric total synthesis of (−)-patchouli alcohol was accomplished in a concise manner. Key reactions include a highly diastereo- and enantioselective formal organocatalytic [4 + 2] cycloaddition reaction, a radical denitration reaction, and an oxidative carboxylation reaction. The formal synthesis of norpatchoulenol was achieved as well.

Graphical abstract: Concise asymmetric total synthesis of (−)-patchouli alcohol

Supplementary files

Article information

Article type
Research Article
Submitted
10 6月 2017
Accepted
07 7月 2017
First published
07 7月 2017
This article is Open Access
Creative Commons BY-NC license

Org. Chem. Front., 2017,4, 2031-2033

Concise asymmetric total synthesis of (−)-patchouli alcohol

G. Xu, G. Lin and B. Sun, Org. Chem. Front., 2017, 4, 2031 DOI: 10.1039/C7QO00459A

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements