Issue 22, 2016

Hypervalent iodine(iii) fluorinations of alkenes and diazo compounds: new opportunities in fluorination chemistry

Abstract

The fluorination of organic molecules is a rapidly evolving and exciting field in synthesis, which still poses huge challenges despite the advances made in the past decades. Hypervalent iodine(III) reagents, which have already proven their versatility as synthetic tools in organic chemistry, are currently on the rise in fluorination chemistry. With their ability to break new mechanistic grounds, they grant access to completely new reactivities and thus also to novel fluorinated structural scaffolds. This review aims to provide an overview of the achievements made in the iodine(III) mediated fluorinations of aliphatic Csp2–carbon atoms with special focus on the opportunities provided by this exciting class of hypervalent substances.

Graphical abstract: Hypervalent iodine(iii) fluorinations of alkenes and diazo compounds: new opportunities in fluorination chemistry

Article information

Article type
Review Article
Submitted
06 五月 2016
First published
15 七月 2016

Chem. Soc. Rev., 2016,45, 6270-6288

Hypervalent iodine(III) fluorinations of alkenes and diazo compounds: new opportunities in fluorination chemistry

S. V. Kohlhepp and T. Gulder, Chem. Soc. Rev., 2016, 45, 6270 DOI: 10.1039/C6CS00361C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements