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This article contains 14 page(s)
Abstract | Cited by

This review article comprehensively profiles all literature reports (2015–2018) related to the detrifluoroacetylative in situ generation of fluorine-containing enolates and their reactions with electrophilic reagents. The innovative facets of this unconventional methodology and its synthetic generality for the preparation of fluorine-containing compounds of high medicinal value are highlighted.

Graphical abstract: Chemistry of detrifluoroacetylatively in situ generated fluoro-enolates

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