Issue 6, 2011

Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

Abstract

We report the effect of carboxyl functionalization of graphene in pacifying its strong hydrophobic interaction with cells and associated toxic effects. Pristine graphene was found to accumulate on the cell membrane causing high oxidative stress leading to apoptosis, whereas carboxyl functionalized hydrophilic graphene was internalized by the cells without causing any toxicity.

Graphical abstract: Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

Supplementary files

Article information

Article type
Communication
Submitted
14 二月 2011
Accepted
15 四月 2011
First published
12 五月 2011

Nanoscale, 2011,3, 2461-2464

Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

A. Sasidharan, L. S. Panchakarla, P. Chandran, D. Menon, S. Nair, C. N. R. Rao and M. Koyakutty, Nanoscale, 2011, 3, 2461 DOI: 10.1039/C1NR10172B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements