Themed collection Journal of Materials Chemistry B Recent Review Articles

A schematic electrohydrodynamics-driven SERS platform to profile four proteins on sEVs to generate a unique molecular signature for lung cancer stratification.

Kim et al. present a small-molecule photosensitizer, LuCXB, which combines a COX-2 inhibitor (celecoxib) with a near-infrared lutetium texaphyrin photocatalyst and was loaded CD133-aptamer functionalized exosome for cancer stem cells targeting.

Schematic illustration of the E-NoM platform. The workflow for the simultaneous detection of four viral antigens during the infection process.

A new perspective for the study/treatment of neurological conditions using in vivo photopharmacology is presented, including initial experimental and computational data.

Colloidal photonic crystals exhibit unique properties that make them ideal for biological applications. This perspective summarizes the primary properties, the strategies, and recent advancements for biological applications.

Steric protection of a long-wavelength dye, by covalent steric appendage or non-covalent encapsulation, produces enhanced photostability, increased fluorescence brightness, decreased self-aggregation, and superior pharmacokinetic profile.

Versatile water-soluble cyclodextrin polymers can be easily prepared from naturally occurring monomers upon polycondensation in the presence of crosslinking agents. We consider their potential use in combination therapies and the hurdles faced.

Intelligent delivery of lipid nanoparticles can be achieved through rational design of protein corona as a “troublemaker”.

Advances in bioactive regenerative polymeric scaffolds continue to be made with new materials and methods of characterization.

Micro/nanomotor swarms propelled by diverse mechanisms.

Intestinal retentive devices (IRDs) are devices designed to anchor within the lumen of the intestines for long-term residence in the gastrointestinal tract.

This article reviews the application of biomaterials in combination with immunotherapy to enhance the localized treatment of tumors, along with the current challenges and future development directions in this field.

Zwitterionic polymers exhibit exceptional protein resistance due to their hydration layer. Both experimental and computational techniques offer insights into the hydration effect and underlying mechanisms.

This review explores nanoparticles in image-guided thermal therapy, highlighting their targeted treatment potential, temperature feedback, nanomaterial architectures, and applications in hyperthermia and precision medicine.

The common ways and various materials used for modulating electronic band structure for SDT are summarized.

This review summarizes the classification and methods for the fabrication of emerging 2D nanomaterials and emphasizes their distinctive properties and biomedical applications that distinguish them from traditional nanomaterials.

This review first outlines the advantages of fluorescence imaging in the NIR-II region, followed by a comprehensive overview of recent advancements in NIR-II fluorophores and their versatile applications in biomedical imaging.

This review aims to provide an overview on the application of BNC-based composites for advanced wound healing and dressings.

The recent progress of various Cu-based nanocatalysts in cancer therapy was reviewed, especially the remarkable achievements in catalytic treatment of cancer in the tumor microenvironment through CDT and CDT-involved multimodal synergies.

Enhancing cell-material interactions through surface engineering to create biomimetic environments and extend implant life.

A comprehensive overview of bioactive glass–polymer nanocomposites highlighting the various fabrication strategies, the materials involved and the major biomedical applications.

We summarized the advantages and advanced applications of fluorescence sensing technology compared with other analytical techniques, as well as the challenges and prospects of current application in the field of TCM quality evaluation.

Design and application of various pH-responsive DNA nanostructures for tumor-targeted strategies toward extracellular and intracellular environments are comprehensively reviewed. Their potential and challenges are also critically discussed.

Cuproptosis is a regulated form of cell death induced by the accumulation of metal ions and is closely linked to aspects of cellular drug resistance, cellular metabolism, and signalling pathways.

Nanomaterials made from 2D semiconductors and biomolecules are reviewed. Cell-nanoparticle interactions are examined in recent simulations. These nanomaterials and MD simulations reveal novel mechanisms and enable cancer drug delivery and targeting.

Nanomaterials for modulating tumor-associated macrophages in photothermal therapy.

Nanobiopolymers in cancer therapeutics offer sustainable and targeted drug delivery with controlled release, enhancing treatment efficacy while ensuring sustainability and biodegradability for improved patient care.

AI-driven precision subcellular navigation with fluorescent probes.

The convergence of nanotechnology and cancer therapeutics has opened new frontiers in the development of advanced drug delivery systems.

Hydrophilicity of implantable biomaterials can facilitate osteoimmunomodulation through influencing proteins adsorption, blood clotting, neutrophils activation, macrophages polarization, angiogenesis and osteogenesis to enhance osseointegration.

This review summarizes recent advances in piezoelectric materials for anti-infective and regenerative therapies. It highlights antibacterial mechanisms and discusses their anti-infective bioapplications.

Key intracellular in situ synthesis processes, including the synthesis of near-infrared fluorescent dyes, intracellular oxidative cross-linking, polymerization, and bioorthogonal reactions, as well as their biomedical applications were summarized.

The need to enhance the precision and specificity of therapeutic nanocarriers has led to the development of nanoscale peptide assemblies capable of sensing and responding to disease-related analytes.

MOFs can act as cargo-carriers, nano-enzymes, and magnetic MOFs. CAPs, interacting with cell receptors to generate primary and secondary ¹O₂, may synergize with MOFs for oncotherapy via acting as cargos, substrates, and magnetic sensing agents.

Prodrugs, activated at the tumor site, offer targeted treatment but may still cause unintended cytotoxicity. This review explores the combination of bioorthogonal reactions with prodrug strategies to improve safety and efficacy.

The review highlights the potential of RGD-conjugated AuNPs in cancer diagnosis and treatment, including breast cancer. It emphasizes the need for further research to fully realize this technology’s potential and inspire future investigations.

Citric acid-based biomaterials have the advantages of simple synthesis, controllable structure, good biocompatibility, and biomimetic viscoelastic mechanical behavior, which have a wide range of applications in the field of biomedical engineering.

Chitosan bio-adhesives bond strongly with various biological tissues, such as skin, mucosa, and internal organs.

Several major surface modification technologies for Ti-based implants.

SAC & SAzymes, an innovative tool for early Alzheimer detection, effectively bridging traditional diagnostic methods with advanced technologies, enable highly sensitive and selective identification of biomarkers, enhancing diagnostic accuracy.

Advanced approaches to alleviate hypoxic and oxidative stress in cardiovascular diseases.

Presented in this review are recent advancements in bioinspired peptide and polyamino acid assemblies as inhibitors of quorum sensing (Agr, Com, PlcR, Rgg, and NPrR) in diverse microbial communities.

Melanoma is one of the most significant and dangerous superficial skin tumors with a high fatality rate, thanks to its high invasion rate, drug resistance and frequent metastasis properties.

This review discusses phototherapeutic nanosystems for oral cancer, emphasizing diverse drug delivery systems, advanced photodynamic therapy approaches, and combination therapies.

DNA computing is a key molecular method in biological analysis. This review highlights advancements in DNA logic systems, material innovations, and applications in imaging, diagnosis, and treatment, addressing challenges and future directions.

This review summarizes various probes for imaging LDs in the fatty liver process using different excitation imaging modes and emission wavelengths, as well as analyzing the achievements, challenges and future development trends in this field.

This review presents the various enzyme immobilization techniques and highlight their application in biosensing, bio-catalysis, drug delivery, and cancer therapy.

This review covers advanced diabetic wound dressing materials, including chitosan–alginate hydrogels, nanofiber mats, and core–shell nanostructures, highlighting the role of nanotechnology and biomimetic scaffolds in improving healing outcomes.

High-throughput and label-free protein nanopore-based sensors with engineering strategies are extensively used to identify public health hazardous substances with single channel recording.

Bone regeneration materials combined with EGCG include natural polymer, synthetic polymer, bioceramic, metal, hydrogel and metal–EGCG networks. Currently, the above materials have been widely studied in the field of medicine.

Schematic diagram of the device, mechanism and biomedical application of electrodeposition for the preparation of bioactive coatings on the surface of titanium implants for bone repair.

Compared to traditional therapies, tumor immunotherapy has received a lot of attention and research focus due to its potential to activate both innate and adaptive immunity, cause low toxicity to normal tissue, and induce long-term immune activity.

Prostate cancer (PCa) is one of the most common malignant neoplasms affecting the male population.

Wound infections, marked by the proliferation of microorganisms at surgical sites, necessitate the development of innovative wound dressings with potent bactericidal properties to curb microbial growth and prevent bacterial infiltration.

Endocytosis efficiency is a prerequisite for the therapeutic efficacy of nanoparticle-based cancer therapy. This review elucidates the physicochemical design, anti-cancer effects and endocytic mechanism of multiple endocytosis-oriented nanoparticles.

The silk protein elicits ambivalent, both mild inflammatory and anti-inflammatory immune responses for biomedical applications that can be attributed to surface chemistry, protein conformation, source of origin, and association with other proteins.

Innovative tooth whitening strategies based on advanced oxidation processes.

The unique roles of nanozymes in enhancing immunotherapy through disrupting tumor metabolism and mediating combination therapies.

This review comprehensively explores the application of nanotechnology for antifungal therapy, particularly focusing on enhancing interaction with fungi, stimuli-responsive drug release in fungal infected tissues, and crossing biological barriers.

To broaden the application of antibacterial materials in nanomedicine, understanding the complex mechanisms and inherent properties is crucial. This review summarizes the advancements in computational and theoretical research in this emerging field.

The integration of nanotechnology and medicine is a significant trend in modern healthcare, with a particular focus on its utilization in atherosclerosis imaging, presenting immense potential for advancement.

Aptamers are oligonucleotide sequences that can connect to particular target molecules, similar to monoclonal antibodies.

Acute kidney injury (AKI) is a severe clinical syndrome characterized by rapid deterioration of renal function caused by a variety of pathogeneses.

Bioengineered 3D breast cancer model using responsive decellularized scaffold.

This review summarizes the recent advancements in biomedical applications of dual-/multi-organelle-targeted aggregation-induced emission (AIE) probes, focusing on their in situ induction of oxidative stress.