Insight into the underlying mechanism of functional Pediococcus acidilactici SWU-HX39 in alleviating hyperuricemia

Juxin He, Xirui Zhang, Huijing Chen, Jianquan Kan, Sameh Awad, Amel A. Ibrahim, Zsolt Zalán and Muying Du

Food Funct., 2025, 16, 6503
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Probiotic interventions with highly acid-tolerant Levilactobacillus brevis strains improve lipid metabolism and gut microbial balance in obese mice

Liping Zhou, Luchan Gong, Zhihao Liu, Jinfeng Xiang, Cong Ren and Yan Xu

Food Funct., 2025, 16, 112
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Assessment of the safety and probiotic properties of Lactiplantibacillus plantarum HYY-DB9 based on comprehensive genomic and phenotypic analysis

Yun-hui Lu, Wan-shi Liang, Rui Wang, Qi-chun Liang, Xin-An Zeng and Yan-yan Huang

LWT, 2024, 203, 116386
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In vivo functional screening on innate immunity of lactic acid bacteria in Galleria mellonella preclinical model: comparative analysis of Lactiplantibacillus plantarum and Lentilactobacillus kefiri

Antonio Guarnieri, Marilina Falcone, Natasha Brancazio, Farwa Mukhtar, Addis Temie Worku, Marco Alfio Cutuli, Vincenzo Pio Iacovino, Sonia Ganassi, Antonio De Cristofaro, Roberto Di Marco and Giulio Petronio Petronio

Front. Cell. Infect. Microbiol., 2025, 15
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Comparative analysis of hyperuricemia induction methods and probiotic interventions in mice

Yanbo Wang, Huijiao Zhang, Shujun Liu, Sheng Sun, Weibin Ren, Tao Wang, Shujuan Zhang, Hangping Yao, Changzhong Jin and Nanping Wu

Current Research in Microbial Sciences, 2025, 9, 100422
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Exploring the anti-inflammatory potential of Lacticaseibacillus paracasei postbiotics: Mechanistic insights and functional components

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Food Bioscience, 2025, 65, 106105
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Hyperuricemia and the gut microbiota: current research hotspots and future trends

Jingjing Yang, Jing Chen, Dingxiang Li, Qin Wu, Yanan Zhang, Yujia Li and Yihui Deng

Front. Microbiol., 2025, 16
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Tryptophan Metabolism-Regulating Probiotics Alleviate Hyperuricemia by Protecting the Gut Barrier Integrity and Enhancing Colonic Uric Acid Excretion

Qianxu Wang, Jiarui Liang, Qianhui Zou, Wenxiu Wang, Guiming Yan, Rui Guo, Tian Yuan, Yutang Wang, Xuebo Liu and Zhigang Liu

J. Agric. Food Chem., 2024, 72, 26746
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Metal–Phenolic Network-Directed Coating of Lactobacillus plantarum: A Promising Strategy to Increase Stability

Haoxuan Zhang, Huange Zhang and Hao Zhong

Foods, 2025, 14, 2277
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Gut microbiota as a new target for hyperuricemia: A perspective from natural plant products

Ling Dong, Fengying Dong, Pingping Guo, Tianxing Li, Yini Fang, Yang Dong, Xiaoxue Xu, Tianqi Cai, Shufei Liang, Xinhua Song, Lingru Li, Wenlong Sun and Yanfei Zheng

Phytomedicine, 2025, 138, 156402
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Protective Effects of a Polyherbal Mixture on Intestinal Injury via the NF-κB Signaling Pathway and Gut Microbiota Modulation in Hyperuricemic Mice

Haoluan Wang, Yu Xi, Fengju Gu, Linlin Peng and Jian Li

Foods, 2025, 14, 1118
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Effect and mechanism of Plantaginis Semen polysaccharides on intestinal microecology in rats with hyperuricemia

Jing Zhao, Yu Fu and Hongbin Qiu

Front. Microbiol., 2025, 16
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Association of dietary inflammatory index with all-cause and cardiovascular disease mortality in hyperuricemia population: A cohort study from NHANES 2001 to 2010

Jingda Huang, Yandong Zhang, Jiajie Li, Huimin Li, Yihui Wei and Mindan Sun

Medicine, 2023, 102, e36300
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Gut microbiota plays a significant role in gout

Zhi-Peng Feng, Xiao-Yan Wang, Hong-Yi Xin, Shao-Li Huang, Hong-Yu Huang, Qiang Xin, Xi-He Zhang and Hong-Wu Xin

Journal of Medical Microbiology, 2024, 73
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Habitual coarse grain intake, gut microbiota, and hyperuricemia in individuals with or at risk of metabolic syndrome: A post-hoc analysis

Juan He, Yifei He, Junqi Li, Guoqing Ma, Yunfeng Li, Jiawen Xie, Chen He, Xinran Feng, Kaizhen Jia, Wei Li, Menghan Wang, Amei Tang, Tian Tian, Xia Liao, Weimin Li, Feng Yan, Ying Zhang, Xiaoxiao Cao, Yuelang Zhang, Nan Yang, Xin Liu and Qian Wang

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Systematic Engineering for Efficient Uric Acid-Degrading Activity in Probiotic Yeast Saccharomyces boulardii

Wenzhuo Wang, Lei Pan, Huansha He, Huiyuan Xue, He Huang, Audrey Mihewi Samosir, Xian Fu and Yue Shen

ACS Synth. Biol., 2025, 14, 2030
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Galangin Protects against Hyperuricemia via Ameliorating Gut–Kidney Axis Dysfunction in Mice

Yanan Zhao, Rui Wang, Ran Cao, Leyao Chen, Lei Chen and Hui Teng

J. Agric. Food Chem., 2025, 73, 13902
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Puerarin-rich compound Puerariae lobatae formulas alleviate hyperuricemia in mice by enhancing renal and intestinal function through regulating gut microbiota

Zhi-Xuan Li, Kai-Wen Kang, Hao Zheng, Dong-Li Li, Ju-Cai Xu, Hui-Qing Lv, Ri-Hui Wu and Li-She Gan

Phytomedicine, 2025, 146, 157115
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Diacylglycerol from camellia oil improves hyperuricemia by inhibiting xanthine oxidase and modulating gut microbiota

Yajuan Chen, Jingjing Xiao, Lingyu Zhang, Jianfei Mu, Jianqiang Wang, Xudong Yu, Li Li, Zhihong Xiao and Ying Liang

International Journal of Biological Macromolecules, 2025, 309, 142451
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Novel FAD-dependent uricase produced by food-sourced Priestia megaterium and activity assessment using hyperuricemia Caenorhabditis elegans

Haiyue Chen, Jun Xu, Han Shi, Xinle Liang and Wenjie Wang

International Journal of Biological Macromolecules, 2025, 329, 147868
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Preclinical Safety Assessment of the Oral Administration of Lactobacillus plantarum GUANKE in Animal Models

Yuewen Yang, Yanlin Zhang, Ruixiang Sun, Wenjuan Du, Yangyang Liu, Lijun Zheng, Zhihong Ren, Ming ding Li and Jianguo Xu

Probiotics & Antimicro. Prot., 2025
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Exploring the therapeutic role of probiotics and prebiotics in mitigating diseases associated with advanced glycation end products

Haiqing Sun, Zhenjiang Liu, Xin Li, Dongxu Wen, Bin Li and Xiaodan Huang

Journal of Applied Microbiology, 2025, 136
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New insights into anti-hyperuricemic effects of novel peptides from Antarctic Krill (Euphausia superba) by Q-Exactive Orbitrap MS-based non-targeted metabolomics

Li Hao, Yulian Ding, Yan Fan, Chensi Xia, Yuqian Meng, Qiannan Jia, Jian Zhang, Changhu Xue and Hu Hou

Food Bioscience, 2024, 59, 104063
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Lactobacillus paracasei 259 alleviates hyperuricemia in rats by decreasing uric acid and modulating the gut microbiota

Chengming Bi, Lanjun Zhang, Jingya Liu and Lianhong Chen

Front. Nutr., 2024, 11
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Limosilactobacillus reuteri HCS02-001 Attenuates Hyperuricemia through Gut Microbiota-Dependent Regulation of Uric Acid Biosynthesis and Excretion

Akbar Hussain, Binqi Rui, Hayan Ullah, Panpan Dai, Kabir Ahmad, Jieli Yuan, Yinhui Liu and Ming Li

Microorganisms, 2024, 12, 637
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Lactiplantibacillus plantarum P101 Ameliorates TiO2 NP-Induced Bone Injury in Young Rats by Remodeling the Gut Microbiota and Inhibiting the Production of Pro-Inflammatory Cytokines

Lixin Xie, Lihua Feng, Xiaomin Tang, Yunping Xu, Hengyi Xu and Yang Liu

IJN, 2024, Volume 19, 11593
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Gut microbiota Lactobacillus johnsonii alleviates hyperuricemia by modulating intestinal urate and gut microbiota-derived butyrate

Rongshuang Han, Zan Wang, Yukun Li, Leyong Ke, Xiang Li, Changgui Li, Zibin Tian and Xin Liu

Chinese Medical Journal, 2025
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Identification and characterization of a novel lactic acid bacteria with uric acid-lowering activity: From screening to genomic analysis and in vivo validation

Yan Chen, Meimei Zhang, Yeqi Bai, Zongchuan Wang, Xing Chen, Shunjing Luo, Tingting Chen and Chengmei Liu

Food Bioscience, 2025, 71, 107220
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Punicalagin attenuates hyperuricemia via restoring hyperuricemia-induced renal and intestinal dysfunctions

Qing-qing Han, Qi-dong Ren, Xu Guo, Mohamed A. Farag, Yu-hong Zhang, Meng-qi Zhang, Ying-ying Chen, Shu-tao Sun, Jin-yue Sun, Ning-yang Li and Chao Liu

Journal of Advanced Research, 2025, 69, 449
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Integrated microbiome and metabolome analysis reveals the key role of taurohyocholate in the treatment of hyperuricemia with Lacticaseibacillus rhamnosus 2016SWU.05.0601

Yanchao Chen, Shenglan Yan, Jing Yang, Yu Zhang, Huayi Suo and Jiajia Song

Food Research International, 2024, 197, 115234
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Comparison of Lactiplantibacillus plantarum isolates from the gut of mice supplemented with different types of nutrients: a genomic and metabolomic study

Ziyan Wang, Zhixuan Zhang, Qiuyue Shi, Songyi Liu, Qiaoli Wu, Ze Wang, Emilaguli Saiding, Jiaojiao Han, Jun Zhou, Rixin Wang and Xiurong Su

Front. Microbiol., 2023, 14
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Effects and mechanisms of kidney bean peptides on uric-lowering activity in oteracil potassium-induced hyperuricemia rats

Tian Zeng, Yongbo She, Tao Hou, Gang Wu and Mengge Zhao

Journal of Functional Foods, 2024, 116, 106172
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The benefits of Lactiplantibacillus plantarum: From immunomodulator to vaccine vector

Joshua Tobias, Stefan Heinl, Kristina Dendinovic, Ajša Ramić, Anna Schmid, Catherine Daniel and Ursula Wiedermann

Immunology Letters, 2025, 272, 106971
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Alteration of gut microbiome in goslings infected with goose astrovirus

Haiqin Li, Qi Su, Duanfeng Fu, Haoyu Huang, Zhihua Lu, Cheng Huang, Yunfeng Chen, Meifang Tan, Jiangnan Huang, Zhaofeng Kang, Qipeng Wei and Xiaoquan Guo

Poultry Science, 2024, 103, 103869
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Monascus Yellow Pigments Ameliorate Hyperuricemia via Dual Mechanisms: Xanthine Oxidase Inhibition and Uric Acid Transporter Modulation (ABCG2, URAT1, and GLUT9)

Furong Xue, Renqin Zhu, Jiaxing Li, Zheng Liu, Lidan Niu, Wei Chen, Chengtao Wang and Jie Zheng

Foods, 2025, 14, 2765
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Effect of probiotics on kidney tissue in an experimental diabetes model

Hülya Çetin, İlknur Lafci, Semih Tan, Bilgin Vural and Saim Özdamar

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Gut Microbiota and Membranous Nephropathy: Novel Molecular Mechanisms and Natural Product Therapeutic Strategies

Xiaohui Zhao, Ziyi Liu and Chongming Wu

Integr Med Nephrol Androl, 2025, 12
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MyD88 exacerbates inflammation‐induced bone loss by modulating dynamic equilibrium between Th17/Treg cells and subgingival microbiota dysbiosis

Po‐Yan Hsiao, Ren‐Yeong Huang, Lin‐Wei Huang, Ching‐Liang Chu, Thomas Van Dyke, Lian‐Ping Mau, Chia‐Dan Cheng, Cheng‐En Sung, Pei‐Wei Weng, Yu‐Chiao Wu, Yi‐Shing Shieh and Wan‐Chien Cheng

Journal of Periodontology, 2024, 95, 764
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Compound probiotics alleviate hyperuricemia-induced renal injury via restoring gut microbiota and metabolism

Ping Liu, Ping Hu, Meiping Jin, Weiqian Sun, Jiajun Wu, Yuyan Tang, Danye Shi, Ting Xie, Yijing Tong, Lusheng Huang, Dongliang Zhang, Hui Zheng, Xudong Xu and Haidong He

BMC Microbiol, 2025, 25
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Anti‑obesity Effects of Lactiplantibacillus plantarum ZNFL-1 by Modulating Gut Microbiota and Lipid Metabolism in High‑Fat Diet‑Induced Mice

Tian Li, Jingxian Zhang, Wenhui Niu, Xiaoling Zhang, Ziqiao Yuan, Leli Wang, Ying Zhang, Lei Wang, Boyang Ji, Lingbo Qu, Yulong Yin and Yongjun Wei

Probiotics & Antimicro. Prot., 2025
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Potential Lactiplantibacillus plantarum AR342 improves hyperuricemia in mice by inhibiting xanthine oxidase activity

Mingyue Xu, Yi Zhou, Zhuoming Tan, Guangqiang Wang, Xin Song, Yijin Yang, Zhiqiang Xiong, Zibo Song, Lianzhong Ai and Yongjun Xia

Food Bioscience, 2025, 71, 107340
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The anti-hyperuricemia effects of polysaccharide from Saccharina japonica through gut-kidney axis

Haoyu Yu, Kai Dong, Mengying Fu, Hui Wang, Jing Wang, Quanbin Zhang, Yang Yue, Lihua Geng and Ning Wu

International Journal of Biological Macromolecules, 2025, 319, 145336
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Alginate ameliorates hyperuricemia in mice by restoring hyperuricemia-induced renal and intestinal dysfunctions

Rongshuang Han, Yukun Li, Yingjie Guo, Minghan Ren, Mengchen Shan, Tao Mao, Xingsi Qi, Yupeng Li, Zibin Tian and Tianyu Fu

International Journal of Biological Macromolecules, 2025, 310, 143422
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The human gut microbiota and uric acid metabolism: genes, metabolites, and diet

Lei Sun, Min Zhang, Jianxin Zhao, Wei Chen and Gang Wang

Critical Reviews in Food Science and Nutrition, 2025, 65, 7612
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Lactiplantibacillus plantarum in fermented beverages: Properties, mechanisms, and future prospects

Mingxin Lin, Shuiqing Lin, Hui He, Yayin Yu, Jinmei Hu and Lin Zhou

Journal of Functional Foods, 2025, 129, 106864
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Aggression and Justice Involvement: Does Uric Acid Play a Role?

Alan C. Logan and Pragya Mishra

Brain Sciences, 2025, 15, 268
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Lactiplantibacillus plantarum L47 and inulin affect colon and liver inflammation in piglets challenged by enterotoxigenic Escherichia coli through regulating gut microbiota

Jingna Miao, Leihong Cui, Hui Zeng, Meixin Hou, Jingxuan Wang and Suqin Hang

Front. Vet. Sci., 2024, 11
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Flavonoid-rich extract of Paederia scandens (Lour.) Merrill improves hyperuricemia by regulating uric acid metabolism and gut microbiota

Yuyi Liu, Shanling Sheng, Linye Wu, Huixian Wang, Hui Xue and Ruimin Wang

Food Chemistry, 2025, 471, 142857
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Isoliquiritigenin Promotes the Repair of High Uric Acid‐Induced Vascular Injuries

Hongyan Zhou, Xinyu Song, Yingying Tian, Lili Zhao, Jingyi Yang, Fangfu Ye, Ting Cao and Jiayu Zhang

Smart Medicine, 2025, 4
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Lactobacillus plantarum LLY-606 Supplementation Ameliorates the Cognitive Impairment of Natural Aging in Mice: The Potential Role of Gut Microbiota Homeostasis

Renjie Shi, Jin Ye, Hua Fan, Xinyun Hu, Xiaoning Wu, Danna Wang, Beita Zhao, Xiaoshuang Dai and Xuebo Liu

J. Agric. Food Chem., 2024, 72, 4049
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9-Hydroxy-8-oxypalmatine, a novel liver-mediated oxymetabolite of palmatine, alleviates hyperuricemia and kidney inflammation in hyperuricemic mice

Xiaoyan Wu, Ronglei Huang, Gaoxiang Ai, Hanbin Chen, Xingdong Ma, Jiana Zhang, Qiting Huang, Jiayi Lao, Huiyuan Zeng, Chuwen Li, Jianhui Xie, Yucui Li, Ziren Su, Jiannan Chen and Xiaoqi Huang

Journal of Ethnopharmacology, 2024, 335, 118606
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Weizmannia coagulans BC99 alleviates hyperuricemia and oxidative stress via DAF-16/SKN-1 activation in Caenorhabditis elegan

Yinyin Gao, Cheng Li, Junfei Li, Mengyao Duan, Xuan Li, Lina Zhao, Ying Wu and Shaobin Gu

Front. Microbiol., 2024, 15
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