Issue 37, 2023

Red emissive carbon dots: a promising next-generation material with intracellular applicability

Abstract

The accidental discovery of carbon dots (CDs) back in 2004 has led to their widespread use in the biomedical field. CDs have demonstrated their effectiveness in reporting 3D structures of biological specimens, identifying normal and cancer cells, and even detecting analytes within cells. However, the limitations of blue-green emitting CDs, such as their shallow penetration, photodamage, and auto-fluorescence, have hindered their practical applications. To overcome these limitations, red emissive CDs (RCDs) have been developed, which have deep tissue penetration, minimal photo-damage, low auto-fluorescence, and high imaging contrast. In this article, we present a thorough review on the use of RCDs in biomedical applications, including in vivo and in vitro bioimaging, photoacoustic imaging, monitoring temperature and polarity changes in living cells, tumour therapy, and drug delivery. With the rapid progress being made in the development of RCDs for intracellular applications, their clinical application is expected to become a reality in the near future.

Graphical abstract: Red emissive carbon dots: a promising next-generation material with intracellular applicability

Article information

Article type
Review Article
Submitted
18 6月 2023
Accepted
12 8月 2023
First published
14 8月 2023

J. Mater. Chem. B, 2023,11, 8848-8865

Red emissive carbon dots: a promising next-generation material with intracellular applicability

K. Warjurkar, S. Panda and V. Sharma, J. Mater. Chem. B, 2023, 11, 8848 DOI: 10.1039/D3TB01378B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements