Issue 42, 2018

Light-driven self-powered biosensor for ultrasensitive organophosphate pesticide detection via integration of the conjugated polymer-sensitized CdS and enzyme inhibition strategy

Abstract

Herein, a light-driven self-powered biosensor based on a photoelectrochemical enzymatic fuel cell (PEFC) was proposed for ultrasensitive organophosphate pesticide (OP) detection. To construct this fuel cell, poly(3,4-ethylenedioxythiophene)-sensitized CdS quantum dot (PEDOT/CdS) photoanode and multiwalled carbon nanotubes/gold nanoparticals/bilirubin oxidase (CNTs/AuNPs/BOD) biocathode were elaborately designed. Initially, the enzyme acetylcholinesterase (AChE) immobilized on the CdS/PEDOT photoanode could hydrolyze acetylthiocholine iodide (ATCh) into thiocholine as the electron donor to enhance the charge separation efficiency; thus, PEFC produced relatively high open circuit voltage (EOCV) upon illumination. OPs could inhibit the AChE enzymatic catalytic activity on hydrolysis, and in this case, a smaller EOCV obtained. Thus, based on the constructed PEFC, self-powered biosensing of OPs was realized, and the detection limit was as low as 0.012 ng mL−1 (S/N = 3), which was comparable or superior to those of the reported methods. In this study, we not only constructed a facile, ultrasensitive and low-cost sensing platform for OP detection, but also provided an ingenious idea for designing light-driven self-powered biosensing based on PEFC.

Graphical abstract: Light-driven self-powered biosensor for ultrasensitive organophosphate pesticide detection via integration of the conjugated polymer-sensitized CdS and enzyme inhibition strategy

Supplementary files

Article information

Article type
Paper
Submitted
30 8月 2018
Accepted
27 9月 2018
First published
28 9月 2018

J. Mater. Chem. B, 2018,6, 6842-6847

Light-driven self-powered biosensor for ultrasensitive organophosphate pesticide detection via integration of the conjugated polymer-sensitized CdS and enzyme inhibition strategy

P. Gai, S. Zhang, W. Yu, H. Li and F. Li, J. Mater. Chem. B, 2018, 6, 6842 DOI: 10.1039/C8TB02286K

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