Issue 15, 2024

Two-dimensional metal organic frameworks in cancer treatment

Abstract

With large specific surface area, controllable pore size, increased active sites, and structural stability, two-dimensional metal organic frameworks (2D MOFs) have emerged as promising nanomedicines in cancer therapy. These distinctive features make 2D MOFs particularly advantageous in cancer treatment and the corresponding application has gained considerable popularity, signifying significant application potential. Herein, recent advances in various applications including drug delivery and chemotherapy, photodynamic therapy, sonodynamic therapy, chemodynamic therapy, catalytic therapy, and combined therapy were summarized, with emphasis on the latest progress of new materials and mechanisms for these processes. Moreover, the current challenges, potential solutions, and possible future directions are discussed as well.

Graphical abstract: Two-dimensional metal organic frameworks in cancer treatment

Article information

Article type
Review Article
Submitted
19 1月 2024
Accepted
16 5月 2024
First published
17 5月 2024

Mater. Horiz., 2024,11, 3482-3499

Two-dimensional metal organic frameworks in cancer treatment

C. Wang and S. Zhang, Mater. Horiz., 2024, 11, 3482 DOI: 10.1039/D4MH00068D

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