Issue 6, 2024

Antimicrobial activity of safe concentrations of ozone, hydrogen peroxide, and triethylene glycol in air and surfaces

Abstract

Monitoring and control of indoor air hygiene has gained much interest since the COVID-19 pandemic because the airborne route is the main pathway for the spread of SARS-CoV-2 and other pathogens, making it necessary to develop strategies to mitigate airborne transmission of diseases. This work addresses indoor breathable air hygiene by proposing the “in situ” reduction of airborne microorganisms with the nebulization of low and safe concentrations of hydrogen peroxide (H2O2, 0.5 and 1 ppm), ozone (O3, 0.06 and 0.2 ppm), triethylene glycol (TEG, 17.1, 52 and 171.2 ppm), and their combinations. The antimicrobial activity was evaluated in an office room by assessing the viability of commercial extremophile sporulated bacteria and naturally present bacteria and fungi in surfaces and air. All three chemicals individually dispersed reduced the viability of sporulated bacteria and naturally occurring microorganisms. Binary combinations were more effective than individual agents in the case of the H2O2 and O3 mixture against sporulated bacteria, and the O3 and TEG mixture against airborne and surface bacteria. The ternary mixture was the most effective against commercial sporulated bacteria and airborne microorganisms. These results illustrate that the application of low and safe concentrations of antimicrobial compounds in indoor air could be an interesting strategy to reduce infection risk.

Graphical abstract: Antimicrobial activity of safe concentrations of ozone, hydrogen peroxide, and triethylene glycol in air and surfaces

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Article information

Article type
Paper
Submitted
31 10月 2023
Accepted
09 4月 2024
First published
22 4月 2024
This article is Open Access
Creative Commons BY license

Environ. Sci.: Atmos., 2024,4, 620-633

Antimicrobial activity of safe concentrations of ozone, hydrogen peroxide, and triethylene glycol in air and surfaces

J. Truyols-Vives, S. Botella-Grau, J. Mercader-Barceló and H. G. Baldoví, Environ. Sci.: Atmos., 2024, 4, 620 DOI: 10.1039/D3EA00156C

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