Yingcai Hu, Sheng-Yan Yin, Ting Deng and Jishan Li
Chem. Commun., 2024,60, 3047-3050
DOI:
10.1039/D3CC06247C,
Communication
A novel AIEgen molecular probe (N-3QL) with typical AIE effects, good biocompatibility, lysosome targeting, pH activation, excellent photostability, and high brightness was synthesized using two simple synthetic steps. Spectroscopic and cytotoxicity experiments indicate that N-3QL can not only be used for the dynamic monitoring of cancer cell lysosomes, but also for photodynamic therapy (PDT) ablation of cancer cells.