Issue 19, 2023

Ferritin nanocages: a versatile platform for nanozyme design

Abstract

Nanozymes are a class of nanomaterials with enzyme-like activities and have attracted increasing attention due to their potential applications in biomedicine. However, nanozyme design incorporating the desired properties remains challenging. Natural or genetically engineered protein scaffolds, such as ferritin nanocages, have emerged as a promising platform for nanozyme design due to their unique protein structure, natural biomineralization capacity, self-assembly properties, and high biocompatibility. In this review, we highlight the intrinsic properties of ferritin nanocages, especially for nanozyme design. We also discuss the advantages of genetically engineered ferritin in the versatile design of nanozymes over natural ferritin. Additionally, we summarize the bioapplications of ferritin-based nanozymes based on their enzyme-mimicking activities. In this perspective, we mainly provide potential insights into the utilization of ferritin nanocages for nanozyme design.

Graphical abstract: Ferritin nanocages: a versatile platform for nanozyme design

Article information

Article type
Review Article
Submitted
31 1月 2023
Accepted
11 4月 2023
First published
13 4月 2023

J. Mater. Chem. B, 2023,11, 4153-4170

Ferritin nanocages: a versatile platform for nanozyme design

C. Wang, Q. Liu, X. Huang and J. Zhuang, J. Mater. Chem. B, 2023, 11, 4153 DOI: 10.1039/D3TB00192J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements