Issue 35, 2021

DNA-based ribonuclease detection assays

Abstract

Ribonucleases are useful as biomarkers and can be the source of contamination in laboratory samples, making ribonuclease detection assays important in life sciences research. With recent developments in DNA-based biosensing, several new techniques are being developed to detect ribonucleases. This review discusses some of these methods, specifically those that utilize G-quadruplex DNA structures, DNA-nanoparticle conjugates and DNA nanostructures, and the advantages and challenges associated with them.

Graphical abstract: DNA-based ribonuclease detection assays

Article information

Article type
Review Article
Submitted
12 2月 2021
Accepted
15 4月 2021
First published
26 4月 2021

J. Mater. Chem. B, 2021,9, 7023-7029

DNA-based ribonuclease detection assays

A. R. Chandrasekaran, J. Mater. Chem. B, 2021, 9, 7023 DOI: 10.1039/D1TB00300C

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