Issue 57, 2020

Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery

Abstract

Marine organisms have been considered an interesting target for the discovery of different classes of secondary natural products with wide-ranging biological activities. Sponges which belong to the order Dictyoceratida are distinctly classified into 5 families: Dysideidae, Irciniidae, Spongiidae, Thorectidae, and Verticilliitidae. In this review, compounds isolated from Dictyoceratida sponges were discussed with their biological potential within the period 2013 to December 2019. Moreover, analysis of the physicochemical properties of these marine natural products was investigated and the results showed that 78% of the compounds have oral bioavailability potential. This review highlights sponges of the order Dictyoceratida as exciting source for discovery of new drug leads.

Graphical abstract: Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery

Supplementary files

Article information

Article type
Review Article
Submitted
17 5月 2020
Accepted
11 9月 2020
First published
21 9月 2020
This article is Open Access
Creative Commons BY license

RSC Adv., 2020,10, 34959-34976

Marine natural products from sponges (Porifera) of the order Dictyoceratida (2013 to 2019); a promising source for drug discovery

E. R. Abdelaleem, M. N. Samy, S. Y. Desoukey, M. Liu, R. J. Quinn and U. R. Abdelmohsen, RSC Adv., 2020, 10, 34959 DOI: 10.1039/D0RA04408C

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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