Issue 45, 2009

Solid-phase synthesis of protected α-amino phosphonic acid oligomers

Abstract

By establishing both a highly efficient phosphonamidate formation and a RuCp-catalyzed cleavage of an allyl linker, the solid-phase synthesis of Fmoc-(GlyP(OBn))6-OH/DIEA, a protected form of a new type of unnatural peptide α-amino phosphonic acid oligomer (APO), has been realized.

Graphical abstract: Solid-phase synthesis of protected α-amino phosphonic acid oligomers

Supplementary files

Article information

Article type
Communication
Submitted
22 6月 2009
Accepted
30 9月 2009
First published
14 10月 2009

Chem. Commun., 2009, 6985-6987

Solid-phase synthesis of protected α-amino phosphonic acid oligomers

Y. Ishibashi and M. Kitamura, Chem. Commun., 2009, 6985 DOI: 10.1039/B912231A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements