Issue 29, 2023

Chiral amino acid modified boron-dipyrromethene nanoparticles with different photodynamic activities

Abstract

Amino acids are one kind of basic life unit in biological systems. Modification with amino acids may bring interesting properties to the principal molecules. In this work, BDP was modified with L-aspartic acid (Asp) and D-Asp to obtain BDP-LAsp and BDP-DAsp, respectively. The as-synthesized BDPs can self-assemble into uniform nanoparticles (NPs) due to the hydrophilicity of Asp. We found that BDP-LAsp NPs possessed higher photodynamic therapeutic efficacy than BDP-DAsp NPs in fighting against cancer cells and bacteria. This provides a simple design strategy for the modification of photosensitizers in the biomedical field.

Graphical abstract: Chiral amino acid modified boron-dipyrromethene nanoparticles with different photodynamic activities

Supplementary files

Article information

Article type
Paper
Submitted
30 3月 2023
Accepted
15 6月 2023
First published
16 6月 2023

J. Mater. Chem. B, 2023,11, 6853-6858

Chiral amino acid modified boron-dipyrromethene nanoparticles with different photodynamic activities

W. Lei, Q. Wu, H. Wen, Y. Wang, W. Lin, T. Sun and Z. Xie, J. Mater. Chem. B, 2023, 11, 6853 DOI: 10.1039/D3TB00684K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements